ArticleLasers in medical science2020
Clinical attachment level gain of lasers in scaling and root planing of chronic periodontitis: a network meta-analysis of randomized controlled clinical trials.
Article in Lasers in medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07446127 (Evaluation of the Effect of Adjunctive Diode Laser Therapy in Mechanical Scaling and Root Surface Debridement in Non-Surgical Periodontal Therapy), which is not on this map. Cited by 18 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of the Effect of Adjunctive Diode Laser Therapy in Mechanical Scaling and Root Surface Debridement in Non-Surgical Periodontal Therapy
Who cites it
18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Platelet-Rich Plasma (PRP) and Injectable Platelet-Rich Fibrin (i-PRF) in the Non-Surgical Treatment of Periodontitis-A Systematic Review.International journal of molecular sciences · 2024Pooled it
- Clinical and biochemical effect of laser as an adjunct to non-surgical treatment of chronic periodontitis.Oral diseases · 2022Pooled it
- Clinical effectiveness of adjunctive diode laser on scaling and root planing in the treatment of periodontitis: is there an optimal combination of usage mode and application regimen? A systematic review and meta-analysis.Lasers in medical science · 2022Pooled it
- Erbium lasers in non-surgical periodontal therapy: an umbrella review and evidence gap map analysis.Lasers in medical science · 2022Pooled it
- Clinical outcomes of diode laser as an adjunct to nonsurgical periodontal therapy for residual periodontal pockets in mandibular second molars-a randomized controlled clinical trial.Clinical oral investigations · 2023Trial
- Article
- Laser-Assisted Periodontal Therapy versus Traditional Scaling and Root Planing: A Clinical and Microbiological Study.Journal of pharmacy & bioallied sciences · 2025Article
- The Use of Hyaluronic Acid in the Non-Surgical Treatment of Periodontitis-An Umbrella Review.Biomedicines · 2025Review
- Current status and influencing factors of missing appointments in patients with periodontitis: a cross-sectional study.BMC oral health · 2024Article
- Effect of Periodontal Treatment in Patients with Periodontitis and Diabetes: Review of Systematic Reviews with Meta-Analyses in the Last Five Years.Healthcare (Basel, Switzerland) · 2024Review
- Anti-infective Efficacy of Mechanical Debridement with Adjunctive Modalities on Clinical and Cytokine Parameters in Treatment of Chronic Periodontitis: Randomized Controlled Clinical Trial.European journal of dentistry · 2024Article
- Effectiveness of photodynamic therapy on the treatment of chronic periodontitis: a systematic review during 2008-2023.Frontiers in chemistry · 2024Review
- Er:YAG laser-induced damage to a dental composite in simulated clinical scenarios for inadvertent irradiation: an in vitro study.Lasers in medical science · 2022Article
- Effect of Twinlight Laser on the Attachment of Human Gingival Fibroblasts to the Root Surface In Vitro.Medical science monitor : international medical journal of experimental and clinical research · 2022Article
- Clindamycin as an Alternative Option in Optimizing Periodontal Therapy.Antibiotics (Basel, Switzerland) · 2021Review
- Impact of Adjunctive Diode Laser Application to Non-Surgical Periodontal Therapy on Clinical, Microbiological and Immunological Outcomes in Management of Chronic Periodontitis: A Systematic Review of Human Randomized Controlled Clinical Trials.Journal of inflammation research · 2021Review
- Effect of scaling and root planing on the expression of anti-inflammatory cytokines (IL-4, IL-9, IL-10, and IL-13) in the gingival crevicular fluid of electronic cigarette users and non-smokers with moderate chronic periodontitis.Journal of periodontal & implant science · 2020Article
- Applications of Lasers in Refractory Periodontitis: A Narrative Review.Journal of International Society of Preventive & Community DentistryReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this study was to evaluate the clinical attachment level (CAL) gain of Er:YAG, Er,Cr; YSGG, Nd:YAG; and diode laser (DL) as monotherapy or adjunctive to scaling and root planing (SRP) of chronic periodontitis by network meta-analysis (NMA). Randomized controlled clinical trials (RCTs) about lasers applied in SRP of chronic periodontitis were searched from PubMed, Cochrane Library, Web of Science, Ovid, Science Direct, Wan Fang, and China National Knowledge Infrastructure (CNKI) databases up to September 2018 and from references of selected full-texts and related reviews. Standard mean differences and 95% confidence intervals were counted for CAL gain. The random effects NMA were performed in STATA software. There were 25 RCTs about CAL gain at 3 and/or 6 months after lasers were applied in SRP. No inconsistency was detected. Er:YAG as monotherapy gained significantly more CAL at 3 months than did SRP; no significant differences were detected among other comparisons. In terms of CAL gain at 3 months, the ranking result from best to worst was as follows: Er:YAG as monotherapy, DL adjunctive to SRP, Er:YAG adjunctive to SRP, Er,Cr;YSGG as monotherapy, Nd:YAG adjunctive to SRP, and SRP. In terms of CAL gain at 6 months, the ranking result from best to worst was as follows: DL adjunctive to SRP, Nd:YAG adjunctive to SRP, SRP, Er:YAG adjunctive to SRP, and Er:YAG as monotherapy. Laser-assisted periodontal treatment could be superior to SRP alone and could serve as a good adjunctive treatment tool.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.