Evidence map›Paper›PMID 31691026›Full record

ArticlePediatric surgery international2020

Adrenalectomy for non-neuroblastic pathology in children.

Michael D Traynor, Alaa Sada, Geoffrey B Thompson, Christopher R Moir, Irina Bancos, David R Farley, Benzon M Dy, Melanie L Lyden, Elizabeth B Habermann, Travis J McKenzie

Abstract read
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Article in Pediatric surgery international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Adrenocortical carcinoma: Pediatric aspects (Review).Experimental and therapeutic medicine · 2022
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Michael D TraynorDepartment of Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Alaa SadaDepartment of Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Geoffrey B ThompsonDepartment of Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Christopher R MoirDivision of Pediatric Surgery, Mayo Clinic, Rochester, MN, USA.
Irina BancosDivision of Endocrinology, Mayo Clinic, Rochester, MN, USA.
David R FarleyDepartment of Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Benzon M DyDepartment of Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Melanie L LydenDepartment of Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Elizabeth B HabermannDivision of Health Care Policy and Research, Mayo Clinic, Rochester, MN, USA.
Travis J McKenzieDepartment of Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA. mckenzie.travis@mayo.edu.
Mayo Clinic · USMayo Clinic in Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdrenalectomy for non-neuroblastic pathologies in children is rare with limited data on outcomes. We reviewed our experience of adrenalectomy in this unique population.

methodsRetrospective study of children (age ≤ 18) who underwent adrenalectomy with non-neuroblastic pathology from 1988 to 2018. Clinical and operative details of patients were abstracted. Outcomes included length of stay and 30-day postoperative morbidity.

resultsForty children underwent 50 adrenalectomies (12 right-sided, 18 left-sided, 10 bilateral). Six patients (15%) presented with an incidental adrenal mass while 4 (10%) had masses found on screening for genetic mutations or prior malignancy. The remaining 30 (75%) presented with symptoms of hormonal excess. Nineteen patients (48%) underwent genetic evaluation and 15 (38%) had genetic predispositions. Diagnoses included 9 patients (23%) with pheochromocytoma, 8 (20%) with adrenocortical adenoma, 8 (20%) with adrenocortical carcinoma, 7 (18%) with adrenal hyperplasia, 2 (5%) with metastasis, and 6 (14%) with additional benign pathologies. Of 50 adrenalectomies, twenty-five (50%) were laparoscopic. Median hospital length of stay was 3 days (range 0-11). Post-operative morbidity rate was 17% with the most severe complication being Clavien-Dindo grade II.

conclusionAdrenalectomy for non-neuroblastic pathology can be done with low morbidity. Its frequent association with genetic mutations and syndromes requires surgeons to have knowledge of appropriate pre-operative testing and post-operative surveillance.

Indexed as

AdolescentAdrenalectomyAdrenal Gland NeoplasmsChildFemaleHumansLaparoscopyLength of StayMalePheochromocytomaPostoperative PeriodRetrospective StudiesAdrenocortical carcinomaEndocrineLaparoscopic adrenalectomyPediatric adrenalectomyPheochromocytomaPrimary pigmented nodular adrenocortical disease (PPNAD)

Identifiers

PMID31691026
OpenAlexW2983013380

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.