Evidence map›Paper›PMID 31691009›Full record

ArticleVirchows Archiv : an international journal of pathology2019

Cause of death and significant disease found at autopsy.

Niklas Friberg, Oscar Ljungberg, Erik Berglund, David Berglund, Richard Ljungberg, Irina Alafuzoff, Elisabet Englund

Open access · hybridAbstract read
In one paragraph

Article in Virchows Archiv : an international journal of pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Implementation of post-mortem examinations within a large population-based cohort: results from the Hamburg City Health Study.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
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  3. Observational
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  11. Ageing-Related Neurodegeneration and Cognitive Decline.International journal of molecular sciences · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Pulmonary embolism at autopsy in cancer patients.Journal of thrombosis and haemostasis : JTH · 2021
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Niklas FribergDepartment of Immunology, Genetics and Pathology, Uppsala University, Dag Hammarskjölds väg 20, 751 85, Uppsala, Sweden. niklas.friberg@gmail.com.ORCID https://orcid.org/0000-0002-7657-7821
Oscar LjungbergDepartment of Clinical Sciences, Division of Oncology and Pathology, Lund University, Sölvegatan 25, 221 85, Lund, Sweden.
Erik BerglundDivision of Transplantation Surgery, CLINTEC, Karolinska Institute, Department of Transplantation Surgery, Karolinska University Hospital, Stockholm, Sweden.
David BerglundDepartment of Immunology, Genetics and Pathology, Uppsala University, Dag Hammarskjölds väg 20, 751 85, Uppsala, Sweden.
Richard LjungbergDepartment of Clinical Sciences, Division of Oncology and Pathology, Lund University, Sölvegatan 25, 221 85, Lund, Sweden.
Irina AlafuzoffDepartment of Immunology, Genetics and Pathology, Uppsala University, Dag Hammarskjölds väg 20, 751 85, Uppsala, Sweden.
Elisabet EnglundDepartment of Clinical Sciences, Division of Oncology and Pathology, Lund University, Sölvegatan 25, 221 85, Lund, Sweden.
Lund University · SEUppsala University · SEKarolinska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of clinical autopsy has been in decline for many years throughout healthcare systems of developed countries despite studies showing substantial discrepancies between autopsy results and pre-mortal clinical diagnoses. We conducted a study to evaluate over time the use and results of clinical autopsies in Sweden. We reviewed the autopsy reports and autopsy referrals of 2410 adult (age > 17) deceased patients referred to two University hospitals in Sweden during two plus two years, a decade apart. There was a decline in the number of autopsies performed over time, however, mainly in one of the two hospitals. The proportion of autopsy referrals from the emergency department increased from 9 to 16%, while the proportion of referrals from regular hospital wards was almost halved. The autopsies revealed a high prevalence of cardiovascular disease, with myocardial infarction and cerebrovascular lesion found in 40% and 19% of all cases, respectively. In a large proportion of cases (> 30%), significant findings of disease were not anticipated before autopsy, as judged from the referral document and additional data obtained in some but not all cases. In accordance with previous research, our study confirms a declining rate of autopsy even at tertiary, academic hospitals and points out factors possibly involved in the decline.

Indexed as

AutopsyCause of DeathDiagnostic ErrorsFemaleHospitals, UniversityHumansMaleMyocardial InfarctionPrevalenceRetrospective StudiesSwedenAutopsyCause of deathDiagnostic errorReferral quality

Identifiers

PMID31691009
PMCPMC6881421
OpenAlexW2985745071

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.