ArticleCerebral cortex (New York, N.Y. : 1991)2020
The Application of Connectome-Based Predictive Modeling to the Maternal Brain: Implications for Mother-Infant Bonding.
Article in Cerebral cortex (New York, N.Y. : 1991), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 30 citations in OpenAlex.
- Maternal Neuroplasticity: Understanding Brain Changes with Perinatal Depression and Anxiety in Women.Current psychiatry reports · 2026Review
- Distinct neural networks predict cocaine versus cannabis treatment outcomes.Molecular psychiatry · 2023Article
- Reduced hippocampal-cortical connectivity during memory suppression predicts the ability to forget unwanted memories.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Neural activation to infant cry among Latina and non-Latina White mothers.Behavioural brain research · 2023Article
- A critical role of brain network architecture in a continuum model of autism spectrum disorders spanning from healthy individuals with genetic liability to individuals with ASD.Molecular psychiatry · 2023Article
- Connectome-based predictive modeling of trait forgiveness.Social cognitive and affective neuroscience · 2023Article
- Individualized prediction of future cognition based on developmental changes in cortical anatomy.Neuroimage. Reports · 2022Article
- Cerebellar engagement in the attachment behavioral system.Scientific reports · 2022Article
- Interpreting Brain Biomarkers: Challenges and solutions in interpreting machine learning-based predictive neuroimaging.IEEE signal processing magazine · 2022Article
- Social experience alters oxytocinergic modulation in the nucleus accumbens of female prairie voles.Current biology : CB · 2022Article
- Less can be more: Fine tuning the maternal brain.Neuroscience and biobehavioral reviews · 2022Review
- Large-scale functional brain networks of maladaptive childhood aggression identified by connectome-based predictive modeling.Molecular psychiatry · 2022Article
- Maternal perinatal anxiety and neural responding to infant affective signals: Insights, challenges, and a road map for neuroimaging research.Neuroscience and biobehavioral reviews · 2021Review
- Increased resting-state activity in the cerebellum with mothers having less adaptive sensory processing and trait anxiety.Human brain mapping · 2021Article
- Prediction of life satisfaction from resting-state functional connectome.Brain and behavior · 2021Article
- Functional connectivity during frustration: a preliminary study of predictive modeling of irritability in youth.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021Article
- How stress can influence brain adaptations to motherhood.Frontiers in neuroendocrinology · 2021Review
- Identification of a brain fingerprint for overweight and obesity.Physiology & behavior · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Maternal bonding early postpartum lays an important foundation for child development. Changing brain structure and function during pregnancy and postpartum may underscore maternal bonding. We employed connectome-based predictive modeling (CPM) to measure brain functional connectivity and predict self-reported maternal bonding in mothers at 2 and 8 months postpartum. At 2 months, CPM predicted maternal anxiety in the bonding relationship: Greater integration between cerebellar and motor-sensory-auditory networks and between frontoparietal and motor-sensory-auditory networks were associated with more maternal anxiety toward their infant. Furthermore, greater segregation between the cerebellar and frontoparietal, and within the motor-sensory-auditory networks, was associated with more maternal anxiety regarding their infant. We did not observe CPM prediction of maternal bonding impairments or rejection/anger toward the infant. Finally, considering 2 and 8 months of data, changes in network connectivity were associated with changes in maternal anxiety in the bonding relationship. Our results suggest that changing connectivity among maternal brain networks may provide insight into the mother-infant bond, specifically in the context of anxiety and the representation of the infant in the mother's mind. These findings provide an opportunity to mechanistically investigate approaches to enhance the connectivity of these networks to optimize the representational and behavioral quality of the caregiving relationship.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.