ArticleScientific reports2019
Synergistic Antibacterial Effects of Metallic Nanoparticle Combinations.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
68 citing papers in PubMed, 1 synthesis or guideline pooled it, 213 citations in OpenAlex.
- Antibacterial Titanium Implants Biofunctionalized by Plasma Electrolytic Oxidation with Silver, Zinc, and Copper: A Systematic Review.International journal of molecular sciences · 2021Pooled it
- Research progress on nanomaterials in promoting phage function and application.Applied and environmental microbiology · 2026Review
- Mechanochemical synthesis of Ag nanoparticles using ascorbic acid.RSC advances · 2026Article
- Article
- Box-Behnken optimized copper oxide nanoparticles from Thymus vulgaris potentiate efficacy against multidrug-resistant bacterial pathogens and exhibit anticancer activity.Bioresources and bioprocessing · 2026Article
- Mechanisms ofMedicina (Kaunas, Lithuania) · 2026Review
- Avian PathogenicVeterinary sciences · 2025Review
- Bio-assessments of the antibiofilm, antioxidant, and plasmid inhibitory effects of zinc selenide nanoparticles synthesized using Stachys lavandulifolia extract.Scientific reports · 2025Article
- Bactericidal, Virucidal, and Biocompatible Properties of 3D Printed Materials Enhanced with Copper and Zinc Nanoparticles.Global challenges (Hoboken, NJ) · 2025Article
- Combined antimicrobial and anti-inflammatory properties of electrospun PCL nanohybrids infused with metal-turmeric oleoresin and metalcurcuminoids.RSC advances · 2025Article
- Eco-friendly synthesis of copper nanoparticles by usingBiochemistry and biophysics reports · 2025Article
- A drug delivery perspective on nanotechnology-based topical therapeutics for inflammatory skin diseases.Nanomedicine (London, England) · 2025Review
- Assessing the Effects of Surface-Stabilized Zero-Valent Iron Nanoparticles on Diverse Bacteria Species Using Complementary Statistical Models.Journal of functional biomaterials · 2025Article
- Green-based anti-biofilm nanoformulations against bacterial contaminations in nosocomial environments.Heliyon · 2025Article
- The antibacterial efficacy and effect of tungsten nanoparticles (WOGMS hygiene and infection control · 2025Article
- Nanoarchitectonics for synergistic activity of multimetallic nanohybrids as a possible approach for antimicrobial resistance (AMR).Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2024Review
- Synergistic Polymer Coatings with Antibacterial and Antiviral Properties for Healthcare Applications.ACS omega · 2024Article
- Phytochemical Analysis of Silver Nanoparticles ofJournal of pharmacy & bioallied sciences · 2024Article
- Preparation of a novel antibacterial magnesium carbonate coating on a titanium surface and itsRSC advances · 2024Article
- Bioactives from citrus food waste: types, extraction technologies and application.Journal of food science and technology · 2024Review
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metallic nanoparticles have unique antimicrobial properties that make them suitable for use within medical and pharmaceutical devices to prevent the spread of infection in healthcare. The use of nanoparticles in healthcare is on the increase with silver being used in many devices. However, not all metallic nanoparticles can target and kill all disease-causing bacteria. To overcome this, a combination of several different metallic nanoparticles were used in this study to compare effects of multiple metallic nanoparticles when in combination than when used singly, as single elemental nanoparticles (SENPs), against two common hospital acquired pathogens (Staphylococcus aureus and Pseudomonas. aeruginosa). Flow cytometry LIVE/DEAD assay was used to determine rates of cell death within a bacterial population when exposed to the nanoparticles. Results were analysed using linear models to compare effectiveness of three different metallic nanoparticles, tungsten carbide (WC), silver (Ag) and copper (Cu), in combination and separately. Results show that when the nanoparticles are placed in combination (NPCs), antimicrobial effects significantly increase than when compared with SENPs (P < 0.01). This study demonstrates that certain metallic nanoparticles can be used in combination to improve the antimicrobial efficiency in destroying morphologically distinct pathogens within the healthcare and pharmaceutical industry.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.