ArticleScientific reports2019
Programming effects of maternal and gestational obesity on offspring metabolism and metabolic inflammation.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
50 citing papers in PubMed, 74 citations in OpenAlex.
- Maternal Diglyceride Diet Attenuates Selected Metabolic Effects of Maternal High-Fat Feeding in Offspring via Energy Metabolism and Microbiota Modulation.Food science & nutrition · 2026Article
- Postweaning diet affects offspring metabolic outcomes more than maternal diet in male and female mice.Physiological reports · 2026Article
- The Interplay of One-Carbon Metabolism, Mitochondrial Function, and Developmental Programming in Ruminant Livestock.Journal of developmental biology · 2026Review
- Stevioside mitigates metabolic dysregulation in offspring induced by maternal high-fat diet: the role of gut microbiota-driven thermogenesis.Gut microbes · 2025Article
- Recruitment and retention of participants with obesity into a longitudinal birth cohort: the Breastfeeding and Early Child Health (BEACH) study.International journal of obesity (2005) · 2025Article
- Impact of maternal high-fat diet on offspring gut microbiota during short-term high-fat diet exposure in mice.Physiological reports · 2024Article
- Key questions and gaps in understanding adipose tissue macrophages and early-life metabolic programming.American journal of physiology. Endocrinology and metabolism · 2024Review
- Maternal high fat diet induces circadian clock-independent endocrine alterations impacting the metabolism of the offspring.iScience · 2024Article
- Postnatal Consumption of Black Bean Powder Protects against Obesity and Dyslipidemia in Male Adult Rat Offspring from Obese Pregnancies.Nutrients · 2024Article
- Pubertal glyphosate-based herbicide exposure aggravates high-fat diet-induced obesity in female mice.Environmental science and pollution research international · 2024Article
- The effect of chronic, non-pathogenic maternal immune activation on offspring postnatal muscle and immune outcomes.Journal of animal science · 2024Article
- The Effect of Maternal High-Fat Diet on Adipose Tissue Histology and Lipid Metabolism-Related Genes Expression in Offspring Rats.Nutrients · 2024Article
- The dynamic influence of nutrition on prolonged cognitive healthspan across the life course: A perspective review.Neuroscience applied · 2024Review
- Sex-specific impact of maternal obesity on fetal placental macrophages and cord blood triglycerides.Placenta · 2023Article
- Pre-pregnancy body mass index and gut microbiota of mothers and children 5 years postpartum.International journal of obesity (2005) · 2023Article
- Maternal Weight Management to Prevent the Developmental Programming of MAFLD in Offspring of Obese Mothers.Nutrients · 2023Review
- Maternal helminth infection protects offspring from high-fat-diet-induced obesity through altered microbiota and SCFAs.Cellular & molecular immunology · 2023Article
- Maternal Pea Protein Intake Provides Sex-Specific Protection against Dyslipidemia in Offspring from Obese Pregnancies.Nutrients · 2023Article
- Severe gestational diabetes mellitus in lean dams is associated with low IL-1α levels and affects the growth of the juvenile mouse offspring.Scientific reports · 2023Article
- Maternal gut microbiota mediate intergenerational effects of high-fat diet on descendant social behavior.Cell reports · 2022Article
Corrections and comments
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
Abstract
With the increasing prevalence of obesity in women of reproductive age there is a need to understand the ramifications of this on offspring. The purpose of this study is to investigate the programming effects of maternal obesity during preconception and the preconception/gestational period on adiposity and adipose tissue inflammation in offspring using an animal model. Adult female C57Bl/6J mice were assigned either normal diet, high fat diet (HFD) prior to pregnancy, or HFD prior to and through pregnancy. Some offspring were maintained on normal diet while others started HFD later in life. Offspring were assessed for body composition and metabolic responses. Lipid storing tissues were evaluated for expansion and inflammation. Male offspring from the preconception group had the greatest weight gain, most subcutaneous adipose tissue, and largest liver mass when introduced to postnatal HFD. Male offspring of the preconception/gestation group had worsened glucose tolerance and an increase in resident (CD11c
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.