Evidence map›Paper›PMID 31690785›Full record

ArticleScientific reports2019

Trpc1 as the Missing Link Between the Bmp and Ca

Isabelle Néant, Ho Chi Leung, Sarah E Webb, Andrew L Miller, Marc Moreau, Catherine Leclerc

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. The Organizer and Its Signaling in Embryonic Development.Journal of developmental biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Isabelle NéantCentre de Biologie du Développement (CBD), Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, F-31062, Toulouse, France.
Ho Chi LeungDivision of Life Science and State Key Laboratory of Molecular Neuroscience, The HKUST, Clear Water Bay, Hong Kong, PRC.
Sarah E WebbDivision of Life Science and State Key Laboratory of Molecular Neuroscience, The HKUST, Clear Water Bay, Hong Kong, PRC.
Andrew L MillerDivision of Life Science and State Key Laboratory of Molecular Neuroscience, The HKUST, Clear Water Bay, Hong Kong, PRC.
Marc MoreauCentre de Biologie du Développement (CBD), Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, F-31062, Toulouse, France.
Catherine LeclercCentre de Biologie du Développement (CBD), Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, F-31062, Toulouse, France. catherine.leclerc@univ-tlse3.fr.
Hong Kong University of Science and Technology · HKUniversité Toulouse III - Paul Sabatier · FRUniversité Fédérale de Toulouse Midi-Pyrénées · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In amphibians, the inhibition of bone morphogenetic protein (BMP) in the dorsal ectoderm has been proposed to be responsible for the first step of neural specification, called neural induction. We previously demonstrated that in Xenopus laevis embryos, the BMP signalling antagonist, noggin, triggers an influx of Ca

Indexed as

Calcium SignalingNeurogenesisAnimalsBone Morphogenetic Protein Receptors, Type IIBone Morphogenetic ProteinsCell MembraneEmbryo, NonmammalianMembrane PotentialsTRPC Cation ChannelsXenopus laevisXenopus ProteinsBone Morphogenetic Protein Receptors, Type IIBone Morphogenetic ProteinsTRPC1 protein, XenopusTRPC Cation ChannelsXenopus Proteins

Identifiers

PMID31690785
PMCPMC6831629
OpenAlexW2983740940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.