Evidence map›Paper›PMID 31690774›Full record

ArticleScientific reports2019

Impact of humanised isolation and culture conditions on stemness and osteogenic potential of bone marrow derived mesenchymal stromal cells.

Salwa Suliman, Hassan R W Ali, Tommy A Karlsen, Jerome Amiaud, Samih Mohamed-Ahmed, Pierre Layrolle, Daniela E Costea, Jan E Brinchmann, Kamal Mustafa

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Salwa SulimanDepartment of Clinical Dentistry, Centre for Clinical Dental Research, University of Bergen, Bergen, Norway. salwa.suliman@uib.no.
Hassan R W AliDepartment of Clinical Dentistry, Centre for Clinical Dental Research, University of Bergen, Bergen, Norway.
Tommy A KarlsenNorwegian Center for Stem Cell Research, Department of Immunology, Oslo University Hospital Rikshospitalet, Oslo, Norway.
Jerome AmiaudINSERM, UMR 1238, PHY-OS, Laboratory of Bone Sarcomas and Remodeling of Calcified Tissues, Faculty of Medicine, University of Nantes, Nantes, France.
Samih Mohamed-AhmedDepartment of Clinical Dentistry, Centre for Clinical Dental Research, University of Bergen, Bergen, Norway.
Pierre LayrolleINSERM, UMR 1238, PHY-OS, Laboratory of Bone Sarcomas and Remodeling of Calcified Tissues, Faculty of Medicine, University of Nantes, Nantes, France.
Daniela E CosteaGade Laboratory for Pathology, Department of Clinical Medicine, University of Bergen, Bergen, Norway.
Jan E BrinchmannNorwegian Center for Stem Cell Research, Department of Immunology, Oslo University Hospital Rikshospitalet, Oslo, Norway.
Kamal MustafaDepartment of Clinical Dentistry, Centre for Clinical Dental Research, University of Bergen, Bergen, Norway. kamal.mustafa@uib.no.
University of Bergen · NOInserm · FROslo University Hospital · NOHaukeland University Hospital · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Therapeutic potential of human bone marrow stromal/stem cells (hBMSC) must be developed using well defined xenogenic-free conditions. hBMSC were isolated from healthy donors (n = 3) using different isolation and expansion methods. Donor I was isolated and expanded by either bone marrow directly seeded and cells expanded in 10% AB human serum (AB) +5 ng/ml fibroblast growth factor-2 (FGF2) [Direct(AB + FGF

Indexed as

Bone Marrow CellsCell Culture TechniquesCell DifferentiationCell SeparationMesenchymal Stem CellsOsteogenesisAnimalsHeterograftsHumansMesenchymal Stem Cell TransplantationMiceMice, Inbred NODMice, SCID

Identifiers

PMID31690774
PMCPMC6831606
OpenAlexW2983615915

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.