Evidence map›Paper›PMID 31690679›Full record

ArticlemBio2019

Drug-Resistant Epimutants Exhibit Organ-Specific Stability and Induction during Murine Infections Caused by the Human Fungal Pathogen Mucor circinelloides.

Zanetta Chang, Joseph Heitman

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
18.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 205 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Molecular mechanisms that govern infection and antifungal resistance in Mucorales.Microbiology and molecular biology reviews : MMBR · 2024
    Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Journal of fungi (Basel, Switzerland) · 2023
    Review
  19. mBio · 2023
    Article
  20. Heterochromatin and RNAi act independently to ensure genome stability in Mucorales human fungal pathogens.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Zanetta ChangDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Duke University, Durham, North Carolina, USA.
Joseph HeitmanDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Duke University, Durham, North Carolina, USA heitm001@duke.edu.
Duke University · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007171 · NIGMS · DUKE UNIVERSITY · PI KONTOS, CHRISTOPHER D · 1985 to 2021
$31.2M
Structure, function, and evolution of the Cryptococcus MAT locusR01AI050113 · NIAID · DUKE UNIVERSITY · PI HEITMAN, JOSEPH · 2002 to 2024
$8.5M
ROLE OF CALCINEURIN IN C. NEOFORMANS MATING AND FRUITINGR01AI039115 · NIAID · DUKE UNIVERSITY · PI HEITMAN, JOSEPH · 1997 to 2025
$6.7M
Genetics of Cryptococcus sexual reproductionR37AI039115 · NIAID · DUKE UNIVERSITY · PI HEITMAN, JOSEPH · 2011 to 2020
$4.9M
Structural Biological Development of Fungal-Specific Calcineurin InhibitorsR01AI112595 · NIAID · DUKE UNIVERSITY · PI HEITMAN, JOSEPH, SCHUMACHER, MARIA · 2014 to 2017
$2.5M
Structural Biological Development of Fungal-Specific Calcineurin InhibitorsR56AI112595 · NIAID · DUKE UNIVERSITY · PI HEITMAN, JOSEPH, HONG, JIYONG · 2020 to 2020
$669k
NIAID NIH HHS R01 AI039115NIAID NIH HHS R01 AI050113NIAID NIH HHS R01 AI112595NIAID NIH HHS R37 AI039115NIAID NIH HHS R56 AI112595NIGMS NIH HHS T32 GM007171
6 · The paper itself

Abstract

The environmentally ubiquitous fungus

Indexed as

AnimalsAntifungal AgentsDisease Models, AnimalDrug Resistance, FungalEpigenesis, GeneticHumansMaleMiceMice, Inbred BALB CMucorMucormycosisRNA InterferenceSirolimusTacrolimusAntifungal AgentsSirolimusTacrolimusantifungal resistanceepigeneticsfilamentous fungi

Identifiers

PMID31690679
PMCPMC6831780
OpenAlexW2985567791

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.