ArticleThe Journal of biological chemistry2020
Hypoxia drives glucose transporter 3 expression through hypoxia-inducible transcription factor (HIF)-mediated induction of the long noncoding RNA NICI.
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Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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28citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
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Who cites it
28 citing papers in PubMed, 50 citations in OpenAlex.
- Genomic characterization and pathogenicity validation of Mycoplasma ovipneumoniae strains from diseased sheep: insights into potential pathogenic mechanisms of GSWW364.Veterinary research · 2026Article
- HIF-Regulated Pannexin-1 Channel Drives Luminal ATP Accumulation in Kidney Cysts.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- HIF sustain a transcriptional regulatory circuit of EPAS1 expression in renal clear cell carcinoma.Nature communications · 2026Article
- Disease-disease interactions: molecular links of neurodegenerative diseases with cancer, viral infections, and type 2 diabetes.Translational neurodegeneration · 2025Review
- βMedicinal research reviews · 2025Review
- Placental and Fetal Metabolic Reprogramming in Pregnancies with Intrauterine Growth Restriction.Reproductive sciences (Thousand Oaks, Calif.) · 2025Observational
- Prokaryotic organelle mitochondria drive tumorigenesis: "the original sin".Frontiers in oncology · 2025Review
- SLC2A3 promotes head and neck squamous cancer developing through negatively regulating CD8Scientific reports · 2024Article
- USP7 depletion potentiates HIF2α degradation and inhibits clear cell renal cell carcinoma progression.Cell death & disease · 2024Article
- GIP attenuates neuronal oxidative stress by regulating glucose uptake in spinal cord injury of rat.CNS neuroscience & therapeutics · 2024Article
- Divergent epigenetic responses to perinatal asphyxia in severe mental disorders.Translational psychiatry · 2024Article
- Butyrate-mediated Resistance to Trichostatin A Accompanied by Elevated Expression of Glucose Transporter 3 (GLUT3) in Human Colorectal Carcinoma HCT116 Cells.Asian Pacific journal of cancer prevention : APJCP · 2023Article
- Identification of SLC2A3 as a prognostic indicator correlated with the NF-κB/EMT axis and immune response in head and neck squamous cell carcinoma.Channels (Austin, Tex.) · 2023Article
- Hypoxia controls expression of kidney-pathogenicLife science alliance · 2023Article
- User-friendly microfluidic system reveals native-like morphological and transcriptomic phenotypes induced by shear stress in proximal tubule epithelium.APL bioengineering · 2023Article
- Stage-specific coexpression network analysis of Myc in cohorts of renal cancer.Scientific reports · 2023Article
- HIF2 Inactivation and Tumor Suppression with a Tumor-Directed RNA-Silencing Drug in Mice and Humans.Clinical cancer research : an official journal of the American Association for Cancer Research · 2022Article
- Hypoxia Is a Dominant Remodeler of the Effector T Cell Surface Proteome Relative to Activation and Regulatory T Cell Suppression.Molecular & cellular proteomics : MCP · 2022Article
- Identification of molecular mechanism and key biomarkers in membranous nephropathy by bioinformatics analysis.American journal of translational research · 2022Article
- Downregulation of lncRNA APCDD1L-AS1 due to DNA hypermethylation and loss of VHL protein expression promotes the progression of clear cell renal cell carcinoma.International journal of biological sciences · 2022Article
Corrections and comments
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Authors and funding
14 authors at 4 institutions in 3 countries.
Victoria LauerDepartment of Nephrology and Hypertension, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Ulmenweg 18, 91054 Erlangen, Germany.
Steffen GramppDepartment of Nephrology and Hypertension, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Ulmenweg 18, 91054 Erlangen, Germany.
James PlattNDM Research Building, University of Oxford, Old Road Campus, Headington, Oxford OX3 7FZ, United Kingdom.
Veronique LafleurNDM Research Building, University of Oxford, Old Road Campus, Headington, Oxford OX3 7FZ, United Kingdom.
Olivia LombardiNDM Research Building, University of Oxford, Old Road Campus, Headington, Oxford OX3 7FZ, United Kingdom.
Hani ChoudhryDepartment of Biochemistry, Faculty of Science, Center of Innovation in Personalized Medicine, King Fahd Center for Medical Research, King Abdulaziz University, Jeddah, Saudi Arabia.
Franziska KranzDepartment of Nephrology and Hypertension, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Ulmenweg 18, 91054 Erlangen, Germany; Department of Computer Science 9, Friedrich-Alexander-Universität Erlangen-Nürnberg, Cauerstraße 11, 91058 Erlangen, Germany.
Arndt HartmannInstitute of Pathology, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Krankenhausstraße 8-10, 91054 Erlangen, Germany.
Bernd WullichDepartment of Urology and Pediatric Urology, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Krankenhausstraße 12, 91054 Erlangen, Germany.
Atsushi YamamotoNDM Research Building, University of Oxford, Old Road Campus, Headington, Oxford OX3 7FZ, United Kingdom.
Mathew L ColemanInstitute of Cancer and Genomic Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom.
Peter J RatcliffeNDM Research Building, University of Oxford, Old Road Campus, Headington, Oxford OX3 7FZ, United Kingdom.
David R MoleNDM Research Building, University of Oxford, Old Road Campus, Headington, Oxford OX3 7FZ, United Kingdom.
Johannes SchödelDepartment of Nephrology and Hypertension, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Ulmenweg 18, 91054 Erlangen, Germany. Electronic address: johannes.schoedel@uk-erlangen.de.
Friedrich-Alexander-Universität Erlangen-Nürnberg · DEUniversity of Oxford · GBKing Abdulaziz University · SAUniversity of Birmingham · GB
Funding
British Heart Foundation RG/11/1/28684Cancer Research UK 16016Cancer Research UK 24552Cancer Research UK A416016Cancer Research UK FC001501Department of Health RP-2015-06-004Medical Research Council FC001501Medical Research Council MR/N021053/1Wellcome Trust 078333/Z/05/ZWellcome Trust 088182/Z/09/ZWellcome Trust FC001501Wellcome Trust WT091857MA
Abstract
Hypoxia-inducible transcription factors (HIFs) directly dictate the expression of multiple RNA species including novel and as yet uncharacterized long noncoding transcripts with unknown function. We used pan-genomic HIF-binding and transcriptomic data to identify a novel long noncoding RNA
Indexed as
Carcinoma, Renal CellCell Line, TumorCell ProliferationCRISPR-Cas SystemsDNA-Binding ProteinsGene Expression Regulation, NeoplasticGene Knockout TechniquesGlucose Transporter Type 3HumansHypoxia-Inducible Factor 1, alpha SubunitPromoter Regions, GeneticRNA, Long NoncodingRNA Polymerase IITranscriptional ActivationTumor HypoxiaVon Hippel-Lindau Tumor Suppressor ProteinDNA-Binding ProteinsGlucose Transporter Type 3HIF1A protein, humanHypoxia-Inducible Factor 1, alpha SubunitRNA, Long NoncodingRNA Polymerase IISLC2A3 protein, humanVHL protein, humanVon Hippel-Lindau Tumor Suppressor ProteinChIPChIP-sequencing (ChIP-Seq)glucose transportGLUT3hypoxiahypoxia-inducible factor (HIF)long noncoding RNA (long ncRNA, lncRNA)
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.