ArticleParasitology2020
Development of an immunochromatographic device to detect antibodies for rapid diagnosis of human angiostrongyliasis.
Article in Parasitology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 29 citations in OpenAlex.
- Immunodominant IgM Epitopes of theInternational journal of molecular sciences · 2026Article
- Seroprevalence ofFood and waterborne parasitology · 2025Article
- Development of an Immunochromatographic Test to Detect Antibodies in Simulated Whole-Blood Samples for the Diagnosis of Intestinal Capillariasis.The American journal of tropical medicine and hygiene · 2025Article
- Evaluation of an Innovative Rapid Diagnostic Test for Human Strongyloidiasis to Detect Specific IgG Antibody in Whole-Blood Samples.The American journal of tropical medicine and hygiene · 2025Article
- An immunochromatographic test using whole blood for rapid diagnosis of human paragonimiasis and its diagnostic usefulness.Food and waterborne parasitology · 2024Article
- Recent update on cerebral sparganosis: A bibliometric analysis and scientific mapping.Narra J · 2024Article
- Insights into the genetic diversity ofFood and waterborne parasitology · 2024Review
- Immunodiagnostic Detection of Angiostrongylus cantonensis Exposure on Hawaii Island Using Isogeographic 31-kDa Antigen.The American journal of tropical medicine and hygiene · 2023Article
- Neuroangiostrongyliasis: Updated Provisional Guidelines for Diagnosis and Case Definitions.Pathogens (Basel, Switzerland) · 2023Article
- Improved diagnostic sensitivity of human strongyloidiasis using point-of-care mixed recombinant antigen-based immunochromatography.Parasite (Paris, France) · 2023Article
- An Innovative Test for the Rapid Detection of Specific IgG Antibodies in Human Whole-Blood for the Diagnosis ofTropical medicine and infectious disease · 2022Article
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- Comparative assessment of immunochromatographic test kits using somatic antigens from adult Opisthorchis viverrini and IgG and IgG4 conjugates for serodiagnosis of human opisthorchiasis.Parasitology research · 2021Article
- Ten Years of Lateral Flow Immunoassay Technique Applications: Trends, Challenges and Future Perspectives.Sensors (Basel, Switzerland) · 2021Review
- Further studies of neuroangiostrongyliasis (rat lungworm disease) in Australian dogs: 92 new cases (2010-2020) and results for a novel, highly sensitive qPCR assay.Parasitology · 2021Article
- Abdominal angiostrongyliasis can be diagnosed with a immunochromatographic rapid test with recombinant galactin from Angiostrongylus cantonensis.Memorias do Instituto Oswaldo Cruz · 2020Article
- Clinical Course and Optical Coherence Tomography of Ocular Angiostrongyliasis: A Case Report.Journal of current ophthalmologyArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cerebral angiostrongyliasis is a central nervous system disease caused by Angiostrongylus cantonensis and can produce eosinophilic meningitis or meningoencephalitis in humans. Sero-immunological techniques, such as the enzyme-linked immunosorbent assay (ELISA) and immunoblotting, are most commonly used for the diagnosis of human angiostrongyliasis. However, diagnosis in remote areas remains problematic because sophisticated equipment and specialized skills are required. To overcome, we have developed the immunochromatographic test (ICT) kit for rapid serological diagnosis of angiostrongyliasis through the detection of anti-A. cantonensis-specific antibodies in human serum. A recombinant A. cantonensis galectin-2 (rAcGal2) from young adult female worms was used as an antigen for the ICT kit development. Diagnostic values were evaluated and compared using the ELISA. The sensitivity, specificity and positive and negative predictive values of the ICT kit were 87.0, 96.5, 94.6 and 91.4%, respectively, and those of the ELISA were 91.0, 97.2, 95.8 and 94.0%, respectively. The concordance of the ICT kit was 93.9%. We, thus, determined that the ICT kit is sensitive and specific and provides reliable diagnostic results. It is rapid and simple to perform and can be utilized for both point-of-care diagnosis in the bedside laboratory and epidemiological surveys in endemic regions where access to diagnostic equipment is limited.
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