Evidence map›Paper›PMID 31690327›Full record

ArticleHealth and quality of life outcomes2019

Health-related quality of life and its predictors among patients with breast cancer at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia.

Selamawit Gebrehiwot Sibhat, Teferi Gedif Fenta, Beate Sander, Gebremedhin Beedemariam Gebretekle

Open access · goldAbstract read
In one paragraph

Article in Health and quality of life outcomes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  6. Data completeness and quality of emergency triage in Ethiopian public tertiary hospitals: A multicenter study.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2025
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  11. Quality of Life of Emirati Women with Breast Cancer.International journal of environmental research and public health · 2022
    Article
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  20. Quality of life among Ethiopian cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Selamawit Gebrehiwot SibhatSchool of Pharmacy, College of Health Sciences, Addis Ababa University, Zambia Street, Addis Ababa, Ethiopia.
Teferi Gedif FentaSchool of Pharmacy, College of Health Sciences, Addis Ababa University, Zambia Street, Addis Ababa, Ethiopia.
Beate SanderInstitute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada.
Gebremedhin Beedemariam GebretekleSchool of Pharmacy, College of Health Sciences, Addis Ababa University, Zambia Street, Addis Ababa, Ethiopia. gebremedhin.beedemariam@aau.edu.et.ORCID http://orcid.org/0000-0002-2485-505X
Addis Ababa University · ETUniversity Health Network · CA

Funding

Addis Ababa University, School of Graduate Studies lamp-sum money given to all postgraduate students
6 · The paper itself

Abstract

backgroundBreast cancer is the second most prevalent malignancy in Ethiopia and severely affects patients' health-related quality of life (HRQOL). We aimed to assess HRQoL, factors influencing HRQoL, and utilities among breast cancer patients at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia.

methodsA hospital-based cross-sectional study was conducted in Tikur Anbessa Specialized Hospital from December 2017 to February, 2018. A total of 404 breast cancer patients were interviewed using the validated Amharic version of the European Organization for Research and Treatment of Cancer module (EORTC QLQ-C30), EORTC QLQ-BR23, and Euro Quality of Life Group's 5-Domain Questionnaires 5 Levels (EQ-5D-5 L) instruments. Mean scores and mean differences of EORTC- QLQ-C30 and EORTC- QLQ-BR23 were calculated. One-way ANOVA test was employed to determine the significance of mean differences among dependent and independent variables while stepwise multivariate logistic regression was used to identify factors associated with the global quality of life (GQOL). Coefficients and level specific utility values obtained from a hybrid regression model for the Ethiopian population were used to compute utility values of each health state. Data was analyzed using SPSS version 23.

resultsThe mean age of patients was 43.94 ± 11.72 years. The mean score for GQoL and visual analog scale was 59.32 ± 22.94 and 69.94 ± 20.36, respectively while the mean utility score was 0.8 ± 0.25. Predictors of GQoL were stage of cancer (AOR = 7.94; 95% CI: 1.83-34.54), cognitive functioning (AOR = 2.38; 95% CI: 1.32-4.31), pain (AOR = 7.99; 95% CI: 4.62-13.83), financial difficulties (AOR = 2.60; 95% CI: 1.56-4.35), and future perspective (AOR = 2.08; 95% CI: 1.24-3.49).

conclusionsThe overall GQoL of breast cancer patients was moderate. Targeted approaches to improve patients' HRQoL should consider stage of cancer, cognitive functioning, pain, financial status and worries about the patient's future health. This study also provides estimates of EQ-5D utility scores that can be used in economic evaluations.

Indexed as

Quality of LifeAdultBreast NeoplasmsCross-Sectional StudiesEthiopiaFemaleHumansLogistic ModelsMiddle AgedPain MeasurementSurveys and QuestionnairesBreast cancerEORTC-QLQ-BR23EORTC-QLQ-C30EQ5DHealth-related quality of lifeHRQoLUtility

Identifiers

PMID31690327
PMCPMC6833153
OpenAlexW2985517807

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.