Evidence map›Paper›PMID 31690303›Full record

Trial reportBMC surgery2019

Compression therapy following posterior lumbar interbody fusion: a prospective, randomized, clinical study.

Wu Sun, Jing-Hua Gao, Li-Guo Zhu, Wei Xiao, Zhen-Zhong Wang, Ke-Xin Yang, Qing Zhang, Bao-Jian Wang

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wu SunSpine Department 2, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, 100102, People's Republic of China.
Jing-Hua GaoSpine Department 2, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, 100102, People's Republic of China.
Li-Guo ZhuSpine Department 2, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, 100102, People's Republic of China. lgsw@sina.com.ORCID http://orcid.org/0000-0003-2593-7978
Wei XiaoState Key Laboratory of Pharmaceutical New-Tech for Chinese Medicine, Jiangsu Kanion Pharmaceutical Co. Ltd., Lianyungang, 222001, People's Republic of China.
Zhen-Zhong WangState Key Laboratory of Pharmaceutical New-Tech for Chinese Medicine, Jiangsu Kanion Pharmaceutical Co. Ltd., Lianyungang, 222001, People's Republic of China.
Ke-Xin YangSpine Department 2, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, 100102, People's Republic of China.
Qing ZhangSpine Department 2, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, 100102, People's Republic of China.
Bao-Jian WangSpine Department 2, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, 100102, People's Republic of China.

Funding

Basic scientific research project of Chinese Academy of Traditional Chinese Medicine ZZ10-022
6 · The paper itself

Abstract

backgroundWound-related complications are an inevitable issue faced by spinal surgeons. Negative pressure drainage remains the most commonly used method to prevent postoperative hematoma and related complications. This prospective, randomized, controlled study was conducted to evaluate the efficacy of compression therapy following posterior lumbar interbody fusion, with emphasis on pain, anemia, and inflammation.

methodsSixty consecutive patients who have undergone posterior lumbar interbody fusion in the age range 43-78 years, with an average age of 59 years, were selected and randomly assigned into two groups. Factors, such as drainage volume, visual analog scale (VAS) pain score for back pain, white blood cell (WBC) count, red blood cell (RBC) count, hemoglobin (Hb) levels, erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) levels assessed on the 1st, 3rd, and 10th days postoperatively, were compared between the two groups.

resultsThe average follow-up was 6 months, ranging from 3 to 11 months. Drainage volume, VAS score, and CRP levels on the 10th day after the surgery were found to be significantly lower in the treatment group than in the control group. RBC count and Hb levels on the 3rd and 10th postoperative days were observed to be significantly higher in the treatment group than in the control group (P < 0.05). During discharge, the wounds of the patients of the both groups had healed and neither showed any symptoms of infection, hematoma, or necrosis.

conclusionCompression therapy relieves pain, alleviates anemia, and the inflammatory response following posterior lumbar interbody fusion.

trial registrationChiCTR1800015825 on chictr.org.cn, April 23, 2018, the trial registry is Chinese Clinical Trial Registry.

Indexed as

AdultAgedBack PainFemaleHumansInflammationLeukocyte CountLumbar VertebraeLumbosacral RegionMaleMiddle AgedPain MeasurementProspective StudiesSpinal FusionTreatment OutcomeAnemiaCompression therapyLumbar spine surgeryPain

Identifiers

PMID31690303
PMCPMC6833233

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.