Evidence map›Paper›PMID 31690060›Full record

ArticleInternational journal of molecular sciences2019

Maintenance of Type 2 Response by CXCR6-Deficient ILC2 in Papain-Induced Lung Inflammation.

Sylvain Meunier, Sylvestre Chea, Damien Garrido, Thibaut Perchet, Maxime Petit, Ana Cumano, Rachel Golub

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sylvain MeunierUnité de Lymphopoièse, Institut Pasteur, 75015 Paris, France. sylvain.meunier@pasteur.fr.
Sylvestre CheaUnité de Lymphopoièse, Institut Pasteur, 75015 Paris, France. sylvestre.chea@gmail.com.
Damien GarridoUnité de Lymphopoièse, Institut Pasteur, 75015 Paris, France. damiengarrido37@gmail.com.
Thibaut PerchetUnité de Lymphopoièse, Institut Pasteur, 75015 Paris, France. thibaut.perchet@pasteur.fr.
Maxime PetitUnité de Lymphopoièse, Institut Pasteur, 75015 Paris, France. maxime.petit@pasteur.fr.
Ana CumanoUnité de Lymphopoièse, Institut Pasteur, 75015 Paris, France. ana.cumano@pasteur.fr.
Rachel GolubUnité de Lymphopoièse, Institut Pasteur, 75015 Paris, France. rachel.golub@pasteur.fr.
Institut Pasteur · FR

Funding

Agence Nationale de la Recherche ANR-13-ISV1-0003Agence Nationale de la Recherche ANR-18-CE15-0024-01Institut National Du Cancer Role of the immune microenvironment during liver carcinogenesis
6 · The paper itself

Abstract

Innate lymphoid cells (ILC) are important players of early immune defenses in situations like lymphoid organogenesis or in case of immune response to inflammation, infection and cancer. Th1 and Th2 antagonism is crucial for the regulation of immune responses, however mechanisms are still unclear for ILC functions. ILC2 and NK cells were reported to be both involved in allergic airway diseases and were shown to be able to interplay in the regulation of the immune response. CXCR6 is a common chemokine receptor expressed by all ILC, and its deficiency affects ILC2 and ILC1/NK cell numbers and functions in lungs in both steady-state and inflammatory conditions. We determined that the absence of a specific ILC2 KLRG1

Indexed as

AnimalsCells, CulturedInterferon-gammaLymphocyte SubsetsMicePapainPneumoniaReceptors, CXCR6Cxcr6 protein, mouseInterferon-gammaPapainReceptors, CXCR6CXCR6ILC immunityImmunologyLung inflammation

Identifiers

PMID31690060
PMCPMC6862482
OpenAlexW2987870149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.