Evidence map›Paper›PMID 31689949›Full record

ArticleNutrients2019

Discovery of Nobiletin from Citrus Peel as a Potent Inhibitor of β-Amyloid Peptide Toxicity.

Kumju Youn, Seonah Lee, Mira Jun

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Neurotrophic Natural Products.Progress in the chemistry of organic natural products · 2024
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Nobiletin prevents amyloid βMetabolic brain disease · 2022
    Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kumju YounDepartment of Food Science and Nutrition, College of Health Sciences, Dong-A University, 37, Nakdong-daero 550 beon-gil, Saha-gu, Busan 49315, Korea. kjyoun@dau.ac.kr.ORCID 0000-0002-3124-2665
Seonah LeeDepartment of Food Science and Nutrition, College of Health Sciences, Dong-A University, 37, Nakdong-daero 550 beon-gil, Saha-gu, Busan 49315, Korea. seonah_lee@daum.net.ORCID 0000-0001-9205-2905
Mira JunDepartment of Food Science and Nutrition, College of Health Sciences, Dong-A University, 37, Nakdong-daero 550 beon-gil, Saha-gu, Busan 49315, Korea. mjun@dau.ac.kr.
Dong-A University · KR

Funding

Dong-A University Not applicable
6 · The paper itself

Abstract

Increasing evidence has demonstrated that amyloid-β peptide (Aβ), the hallmark of Alzheimer's disease (AD), evokes oxidative and inflammatory cascades, which ultimately lead to the death of neurons. The purpose of the present study is to demonstrate the effect of nobiletin, a representative compound of citrus peel, in preventive and therapeutic approaches against neuronal damage by exposure to Aβ

Indexed as

Amyloid beta-PeptidesAnimalsAntioxidantsApoptosisBiomarkersCaspase 3Cell SurvivalCitrusFlavonesFruitGene Expression RegulationInflammationMitogen-Activated Protein Kinase KinasesNF-kappa BPC12 CellsPeptide FragmentsAmyloid beta-Peptidesamyloid beta-protein (25-35)AntioxidantsBiomarkersCaspase 3FlavonesMitogen-Activated Protein Kinase KinasesNF-kappa BnobiletinPeptide FragmentsAlzheimer’s diseaseamyloid-β peptideinflammationnobiletinoxidative stress

Identifiers

PMID31689949
PMCPMC6893598
OpenAlexW2986029667

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.