Evidence map›Paper›PMID 31689934›Full record

ArticleToxins2019

Investigation of the In-Vivo Cytotoxicity and the In Silico-Prediction of MDM2-p53 Inhibitor Potential of

Yasmina M Abd-Elhakim, Mohamed Abdo Nassan, Gamal A Salem, Abdelkarim Sasi, Adil Aldhahrani, Khaled Ben Issa, Amany Abdel-Rahman Mohamed

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. A flavonoid-rich fraction ofFrontiers in pharmacology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Yasmina M Abd-ElhakimDepartment of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44511, Egypt. yasmina.forensic@yahoo.com.ORCID 0000-0002-3646-6385
Mohamed Abdo NassanLaboratories Technology Department, Turabah University College, Taif University, Turabah 21995, Saudi Arabia. moh_nassan@yahoo.com.
Gamal A SalemDepartment of Pharmacology, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44511, Egypt. gamal_vet_85@yahoo.com.
Abdelkarim SasiDepartment of Chemistry, Faculty of Pharmacy, Misurata University, Misurata 2478, Libya. Kareem.sasi@gmail.com.ORCID 0000-0003-0011-8546
Adil AldhahraniLaboratories Technologie Department, Turaba University College, Taif University, Turabah 21995, Saudi Arabia. adildh@hotmail.com.
Khaled Ben IssaPharmaceutical and Industrial Department, Faculty of Pharmacy, Misurata University, Misurata 2478, Libya. khaledbenissa87@gmail.com.
Amany Abdel-Rahman MohamedDepartment of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44511, Egypt. yasmina_forensic@hotmail.com.
Misurata University · LYTaif University · SAZagazig University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study explored the probable in vivo cardiac and renal toxicities together with in silico approaches for predicting the apoptogenic potential of

Indexed as

AnimalsApoptosisBiomarkersCell SurvivalComputer SimulationEuphorbiaHeartKidneyMaleMolecular Docking SimulationMyocardiumPlant ExtractsProto-Oncogene Proteins c-mdm2RatsRats, WistarTumor Suppressor Protein p53BiomarkersMdm2 protein, ratPlant ExtractsProto-Oncogene Proteins c-mdm2Tumor Suppressor Protein p53anticancerapoptosisdi-(2-ethylhexyl) phthalateEuphorbia peplusMDM2-p53

Identifiers

PMID31689934
PMCPMC6891376
OpenAlexW2989345123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.