Evidence map›Paper›PMID 31689902›Full record

Trial reportNutrients2019

Factors Predicting the Response to a Vitamin D-Fortified Milk in Healthy Postmenopausal Women.

Rebeca Reyes-Garcia, Antonia Garcia-Martin, Santiago Palacios, Nancy Salas, Nicolas Mendoza, Miguel Quesada-Charneco, Juristo Fonolla, Federico Lara-Villoslada, Manuel Muñoz-Torres

Abstract readClinical Trial
In one paragraph

Trial report in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rebeca Reyes-GarciaCentro de Investigación Biomédica en Red sobre Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, 28029 Madrid, Spain. rebeca.reyes.garcia@gmail.com.ORCID 0000-0003-1729-4431
Antonia Garcia-MartinCentro de Investigación Biomédica en Red sobre Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, 28029 Madrid, Spain. garciamartin_t@hmail.com.
Santiago PalaciosPalacios Institute of Women's Health, 28029 Madrid, Spain. santiago.palacios@institutopalacios.com.
Nancy SalasPalacios Institute of Women's Health, 28029 Madrid, Spain. nancy.salas@institutopalacios.com.
Nicolas MendozaDepartment of Obstetrics and Gynecology, University of Granada, 18016 Granada, Spain. NICOMENDOZA@telefonica.net.
Miguel Quesada-CharnecoUnidad de Gestión Clínica Endocrinología y Nutrición, Hospital Universitario San Cecilio de Granada, Avenida de la Innovacion, 18016 Granada, Spain. charneco@me.com.ORCID 0000-0001-8687-5526
Juristo FonollaNutrition Department, Biosearch S.A, 18016 Granada, Spain. juristo.fonollajoya@biosearchlife.com.
Federico Lara-VillosladaResearch and Development Department of Lactalis Puleva, Nutrition Department, Biosearch S.A, 18004 Granada, Spain. federico.laravilloslada@puleva.es.
Manuel Muñoz-TorresCentro de Investigación Biomédica en Red sobre Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, 28029 Madrid, Spain. mmt@mamuto.es.ORCID 0000-0002-9645-3260

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMilk products fortified with vitamin D may constitute an alternative to pharmacological supplements for reaching the optimal levels of serum 25-hydroxyvitamin D [25(OH)D]. Our aim was to analyze the response of serum 25(OH)D and its predictive factors in postmenopausal healthy women after a dietary intervention with a milk fortified with vitamin D and calcium.

methodsWe designed a prospective study including 305 healthy postmenopausal women who consumed a fortified milk with calcium (900 mg/500 mL) and vitamin D3 (600 IU/500 mL) daily for 24 months.

resultsThe 25(OH)D concentrations at 24 months were correlated to weight, to body mass index, to the percentage of fat, triglycerides and to baseline 25(OH)D levels. We found significant differences in the levels of 25(OH)D at 24 months according to baseline 25(OH)D levels (

conclusionsIn healthy postmenopausal women, the improvement in 25(OH)D after an intervention with a fortified milk for 24 months depends mainly on the baseline levels of serum 25(OH)D and on the percentage of body fat.

Indexed as

Food, FortifiedPostmenopauseAgedAnimalsBone DensityFemaleHumansMiddle AgedMilkVitamin D25-hydroxyvitamin DVitamin Dfat massobesitypostmenopausal womenVitamin D

Identifiers

PMID31689902
PMCPMC6893628

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.