Evidence map›Paper›PMID 31689898›Full record

ArticleNutrients2019

Evidence of Human Milk Oligosaccharides in Cord Blood and Maternal-to-Fetal Transport across the Placenta.

Birgit Hirschmugl, Waltraud Brandl, Bence Csapo, Mireille van Poppel, Harald Köfeler, Gernot Desoye, Christian Wadsack, Evelyn Jantscher-Krenn

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

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  9. Combining HPAEC-PAD, PGC-LC-MS, and 1DJournal of agricultural and food chemistry · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Birgit HirschmuglDepartment of Obstetrics and Gynecology, Medical University of Graz, 8036 Graz, Austria. birgit.hirschmugl@medunigraz.at.
Waltraud BrandlDepartment of Obstetrics and Gynecology, Medical University of Graz, 8036 Graz, Austria. waltraud.brandl@medunigraz.at.
Bence CsapoDepartment of Obstetrics and Gynecology, Medical University of Graz, 8036 Graz, Austria. bence.csapo@medunigraz.at.
Mireille van PoppelBioTechMed-Graz, 8010 Graz, Austria. mireille.van-poppel@uni-graz.at.ORCID 0000-0001-5694-4324
Harald KöfelerBioTechMed-Graz, 8010 Graz, Austria. harald.koefeler@medunigraz.at.
Gernot DesoyeDepartment of Obstetrics and Gynecology, Medical University of Graz, 8036 Graz, Austria. gernot.desoye@medunigraz.at.ORCID 0000-0002-5715-3230
Christian WadsackDepartment of Obstetrics and Gynecology, Medical University of Graz, 8036 Graz, Austria. christian.wadsack@medunigraz.at.ORCID 0000-0002-5589-8642
Evelyn Jantscher-KrennDepartment of Obstetrics and Gynecology, Medical University of Graz, 8036 Graz, Austria. evelyn.jantscher-krenn@medunigraz.at.ORCID 0000-0003-3568-891X
Medical University of Graz · ATUniversity of Graz · AT

Funding

Bundesministerium für Bildung, Wissenschaft und Forschung BMWFW-10.420/0005-WF/V/3c/2017European Commission 627056Oesterreichische Nationalbank 16927
6 · The paper itself

Abstract

Human milk oligosaccharides (HMOs) are present in maternal serum in early gestation, raising the question of whether HMOs can cross the placental barrier and reach fetal circulation. Here, we aimed to detect HMOs in cord blood, and assess HMO composition and concentration in relation to maternal HMOs. In an ex-vivo placental perfusion model, we asked whether HMOs can pass over the placenta. Using HPLC, we measured HMOs in maternal serum and matching venous cord blood samples collected at delivery from normal pregnancies (

Indexed as

Maternal-Fetal ExchangeFemaleFetal BloodHumansInfant, NewbornMilk, HumanOligosaccharidesPlacentaPregnancyOligosaccharides2′-fucosyllactosefetal circulationHuman Milk Oligosaccharides (HMOs)placentaplacental transportpregnancysecretor status

Identifiers

PMID31689898
PMCPMC6893815
OpenAlexW2989130362

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.