Evidence map›Paper›PMID 31689372›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019

FAM19A1, a brain-enriched and metabolically responsive neurokine, regulates food intake patterns and mouse behaviors.

Xia Lei, Lili Liu, Chantelle E Terrillion, Senthilkumar S Karuppagounder, Pedro Cisternas, Mark Lay, David C Martinelli, Susan Aja, Xinzhong Dong, Mikhail V Pletnikov and 1 more

Open access · greenAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. CTRP10 is required for optimal motor function.The Journal of biological chemistry · 2026
    Article
  3. Article
  4. Can Adipokine FAM19A5 Be a Biomarker of Metabolic Disorders?Diabetes, metabolic syndrome and obesity : targets and therapy · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Loss of CTRP4 alters adiposity and food intake behaviors in obese mice.American journal of physiology. Endocrinology and metabolism · 2020
    Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Xia LeiDepartment of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Lili LiuDepartment of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Chantelle E TerrillionDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Senthilkumar S KaruppagounderDepartment of Neurology and Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Pedro CisternasDepartment of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Mark LaySolomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
David C MartinelliDepartment of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut, USA.
Susan AjaCenter for Metabolism and Obesity Research, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Xinzhong DongSolomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Mikhail V PletnikovDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
G William WongDepartment of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Johns Hopkins University · USJohns Hopkins Medicine · USHunan University of Science and Technology · CNUConn Health · US

Funding

CTRP and Metabolic ControlR01DK084171 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI Guang William Wong · 2010 to 2026
$8.0M
Mutant DISC 1 and Abnormal Neurodevelopment in Mental IllnessR01MH083728 · NIMH · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI PLETNIKOV, MIKHAIL V · 2009 to 2020
$4.9M
Training Program in NeuroscienceT32NS091018 · NINDS · JOHNS HOPKINS UNIVERSITY · PI JAMES J KNIERIM, Daniel Hans O'Connor · 2015 to 2026
$4.1M
Molecular mechanism of astrocytic vulnerability to adolescent cannabis useR01DA041208 · NIDA · JOHNS HOPKINS UNIVERSITY · PI KAMIYA, ATSUSHI, PLETNIKOV, MIKHAIL V · 2016 to 2020
$2.9M
NIDA NIH HHS R01 DA041208NIDDK NIH HHS R01 DK084171NIMH NIH HHS R01 MH083728NINDS NIH HHS T32 NS091018
6 · The paper itself

Abstract

Cytokines and chemokines play diverse roles in different organ systems. Family with sequence similarity 19, member A1-5 (FAM19A1-A5; also known as TAFA1-5) is a group of conserved chemokine-like proteins enriched in the CNS of mice and humans. Their functions are only beginning to emerge. Here, we show that the expression of

Indexed as

EatingLocomotionSpatial LearningAnimalsCells, CulturedChemokinesCorpus StriatumDopamineExploratory BehaviorFemaleHEK293 CellsHumansMaleMiceMice, Inbred C57BLNorepinephrineChemokinesDopamineNorepinephrineTafa1 protein, mousechemokine-likedopaminelocomotor hyperactivityTAFA1

Identifiers

PMID31689372
PMCPMC6894063
OpenAlexW2988529811

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.