Evidence map›Paper›PMID 31689273›Full record

ReviewCurrent opinion in supportive and palliative care2019

Dealing with prognostic uncertainty: the role of prognostic models and websites for patients with advanced cancer.

David Hui, John P Maxwell, Carlos Eduardo Paiva

Abstract readReview
In one paragraph

Review in Current opinion in supportive and palliative care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. The impact of a web-based prognostic calculator on prognostic confidence in outpatient palliative care.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. Longitudinal patient-reported outcomes and survival among early-stage non-small cell lung cancer patients receiving stereotactic body radiotherapy.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2022
    Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

David HuiDepartment of Palliative Care, Rehabilitation and Integrative Medicine, MD Anderson Cancer Center, Houston, Texas.
John P MaxwellMemorial Inpatient Physician Services, Virginia Mason Memorial Hospital, Yakima, Washington, USA.
Carlos Eduardo PaivaDepartment of Medical Oncology, Barretos Cancer Hospital, Barretos, Brazil.

Funding

Strategies for Persistent Agitated Delirium in Palliative CareR01CA225701 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HUI, DAVID · 2019 to 2022
$1.9M
A Randomized Controlled Trial of Dexamethasone for Dyspnea in Cancer PatientsR01CA214960 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HUI, DAVID · 2017 to 2020
$1.6M
Palliative Therapies for Refractory Delirium in Advanced CancerR21NR016736 · NINR · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HUI, DAVID · 2017 to 2018
$455k
NCI NIH HHS R01 CA214960NCI NIH HHS R01 CA225701NINR NIH HHS R21 NR016736
6 · The paper itself

Abstract

purpose of reviewTo provide an updated overview of prognostic models in advanced cancer and highlight the role of prognostic calculators. RECENT

findingsIn the advanced cancer setting, many important healthcare decisions are driven by a patient's prognosis. However, there is much uncertainty in formulating prognosis, particularly in the era of novel cancer therapeutics. Multiple prognostic models have been validated for patients seen by palliative care and have a life expectancy of a few months or less, such as the Palliative Performance Scale, Palliative Prognostic Score, Palliative Prognostic Index, Objective Prognostic Score, and Prognosis in Palliative Care Study Predictor. However, these models are seldom used in clinical practice because of challenges related to limited accuracy when applied individually and difficulties with model selection, computation, and interpretation. Online prognostic calculators emerge as tools to facilitate knowledge translation by overcoming the above challenges. For example, www.predictsurvival.com provides the output for seven prognostic indexes simultaneously based on 11 variables. SUMMARY: Prognostic models and prognostic websites are currently available to augment prognostication in the advanced cancer setting. Further studies are needed to examine their impact on prognostic accuracy, confidence, and clinical outcomes.

Indexed as

Health Status IndicatorsInternetUncertaintyDecision MakingHumansNeoplasmsNeoplasm StagingPalliative CarePrognosisReproducibility of Results

Identifiers

PMID31689273
PMCPMC7034625

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.