ArticleeLife2019
Dichotomous organization of amygdala/temporal-prefrontal bundles in both humans and monkeys.
Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.
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Who cites it
51 citing papers in PubMed, 1 synthesis or guideline pooled it, 102 citations in OpenAlex.
- A systematic review and meta-analysis of resting-state fMRI in anxiety disorders: Need for data sharing to move the field forward.Journal of anxiety disorders · 2023Pooled it
- Toward multimodal MRI biomarkers of PTSD: functional and structural connectivity signatures in WTC responders.medRxiv : the preprint server for health sciences · 2026Article
- Deep brain stimulation induces white matter remodeling and functional changes to brain-wide networks.Nature neuroscience · 2026Article
- Integrated Representations of Threat and Controllability in the Lateral Frontal Pole.Journal of cognitive neuroscience · 2026Article
- Comparing the Limbic-Frontal Connectome across the Primate Order: Conservation of Connections and Implications for Translational Neuroscience.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Article
- An anthropoid/strepsirrhine divergence in ventral visual stream connectivity.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Human amygdala nuclei show distinct developmental trajectories from adolescence to adulthood in functional integration with prefrontal circuitry.Cell reports · 2025Article
- The inferior fronto-occipital fasciculus: bridging phylogeny, ontogeny and functional anatomy.Brain : a journal of neurology · 2025Review
- The spatial extent of anatomical connections within the thalamus varies across the cortical hierarchy in humans and macaques.bioRxiv : the preprint server for biology · 2025Article
- Frontostriatal Networks Undergo Functional Specialization during Adolescence That Follows a Ventral-Dorsal Gradient: Developmental Trajectories and Longitudinal Associations.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Lateral frontopolar theta-band activity supports flexible switching between emotion regulation strategies.Scientific reports · 2025Article
- Insights into the Neurobiology of Behavioral Inhibition from Nonhuman Primate Models.Current topics in behavioral neurosciences · 2025Review
- Generalising XTRACT tractography protocols across common macaque brain templates.Brain structure & function · 2024Article
- A map of white matter tracts in a lesser ape, the lar gibbon.Brain structure & function · 2024Article
- Evolutionary scaling and cognitive correlates of primate frontal cortex microstructure.Brain structure & function · 2024Article
- Article
- Information-based TMS to mid-lateral prefrontal cortex disrupts action goals during emotional processing.Nature communications · 2024Article
- Nuclei-specific hypothalamus networks predict a dimensional marker of stress in humans.Nature communications · 2024Article
- Anxious individuals shift emotion control from lateral frontal pole to dorsolateral prefrontal cortex.Nature communications · 2023Article
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
The interactions of anterior temporal structures, and especially the amygdala, with the prefrontal cortex are pivotal to learning, decision-making, and socio-emotional regulation. A clear anatomical description of the organization and dissociation of fiber bundles linking anterior temporal cortex/amygdala and prefrontal cortex in humans is still lacking. Using diffusion imaging techniques, we reconstructed fiber bundles between these anatomical regions in human and macaque brains. First, by studying macaques, we assessed which aspects of connectivity known from tracer studies could be identified with diffusion imaging. Second, by comparing diffusion imaging results in humans and macaques, we estimated the patterns of fibers coursing between human amygdala and prefrontal cortex and compared them with those in the monkey. In posterior prefrontal cortex, we observed a prominent and well-preserved bifurcation of bundles into primarily two fiber systems-an amygdalofugal path and an uncinate path-in both species. This dissociation fades away in more rostral prefrontal regions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.