Evidence map›Paper›PMID 31689007›Full record

ArticleObesity (Silver Spring, Md.)2019

Dietary Weight Loss, Exercise, and Inflammation in Older Adults with Overweight or Obesity and Cardiometabolic Disease.

W Jack Rejeski, Anthony P Marsh, Jason Fanning, Walter T Ambrosius, Michael P Walkup, Barbara J Nicklas

Open access · greenAbstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Changes in Weight or Body Composition by Frailty Status: A Pilot Study.Journal of nutrition in gerontology and geriatrics
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

W Jack RejeskiDepartment of Health & Exercise Science, Wake Forest University, Winston-Salem, North Carolina, USA.ORCID 0000-0003-2281-4649
Anthony P MarshDepartment of Health & Exercise Science, Wake Forest University, Winston-Salem, North Carolina, USA.
Jason FanningDepartment of Health & Exercise Science, Wake Forest University, Winston-Salem, North Carolina, USA.
Walter T AmbrosiusDepartment of Biostatistics and Data Science, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Michael P WalkupDepartment of Biostatistics and Data Science, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Barbara J NicklasSection on Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Wake Forest University · US

Funding

Wake Forest Claude D. Pepper OAIC - RenewalP30AG021332 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Denise Kathryn Houston · 2002 to 2026
$36.4M
Intervening on sedentary behavior to prevent weight regain in older adultsR01AG051624 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI NICKLAS, BARBARA J, REJESKI, WALTER JOHN · 2016 to 2020
$3.8M
Translational Training in Aging and Alzheimer’s Disease Related DisordersT32AG033534 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI STEPHEN B. KRITCHEVSKY · 2009 to 2026
$3.6M
Cooperative Lifestyle Intervention Programs (CLIP-II)R18HL076441 · NHLBI · WAKE FOREST UNIVERSITY · PI MARSH, ANTHONY P, REJESKI, WALTER JOHN · 2012 to 2016
$3.1M
Cooperative Lifestyle Intervention ProgramR01HL076441 · NHLBI · WAKE FOREST UNIVERSITY · PI REJESKI, WALTER JOHN · 2005 to 2009
$2.9M
NHLBI NIH HHS R01 HL076441NHLBI NIH HHS R18 HL076441NIA NIH HHS P30 AG021332NIA NIH HHS R01 AG051624NIA NIH HHS T32 AG033534
6 · The paper itself

Abstract

objectiveThis study aimed to examine exercise modality during weight loss on change in inflammation among older adults with overweight or obesity and cardiometabolic disease.

methodsA total of 222 older adults with a mean (SD) age of 66.9 (4.7) years and a mean (SD) BMI of 33.5 (3.5) kg/m

resultsAll groups lost significant weight from baseline to 18 months, with average adjusted changes of -5.5% for WL, -9.0% for WL + AT, and -10.1% for WL + RT. WL + RT and WL + AT lost significantly more weight than WL (P < 0.05). At 18 months, CRP values in WL + RT were significantly lower than WL (2.25 pg/mL vs. 3.38 pg/mL; P = 0.004). The only difference in interleukin-6 was that at 18 months, WL + RT was lower than WL + AT (2.32 pg/mL vs. 2.75 pg/mL; P = 0.03).

conclusionsThe addition of RT during WL was more effective at reducing levels of CRP than WL. Although results were in the expected direction, there was no difference in CRP between WL and WL + AT.

Indexed as

AgedCardiovascular DiseasesDietExerciseFemaleHumansInflammationMaleObesityOverweightWeight Loss

Identifiers

PMID31689007
PMCPMC6941888
OpenAlexW2985446962

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.