Evidence map›Paper›PMID 31687928›Full record

ArticleeLife2019

Modular transcriptional programs separately define axon and dendrite connectivity.

Yerbol Z Kurmangaliyev, Juyoun Yoo, Samuel A LoCascio, S Lawrence Zipursky

Abstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

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  13. Biased cell adhesion organizes a circuit for visual motion integration.bioRxiv : the preprint server for biology · 2023
    Article
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  20. Structure and evolution of neuronal wiring receptors and ligands.Developmental dynamics : an official publication of the American Association of Anatomists · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yerbol Z Kurmangaliyev *Department of Biological Chemistry, Howard Hughes Medical Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, United States.ORCID 0000-0003-4829-2025
Juyoun Yoo *Neuroscience Interdepartmental Program, University of California, Los Angeles, Los Angeles, United States.
Samuel A LoCascio *Department of Biological Chemistry, Howard Hughes Medical Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, United States.
S Lawrence ZipurskyDepartment of Biological Chemistry, Howard Hughes Medical Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, United States.ORCID 0000-0001-5630-7181

Funding

Training Grant in Neurobehavioral GeneticsT32NS048004 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BEARDEN, CARRIE E, OPHOFF, ROEL A · 2004 to 2025
$5.8M
Genetic programs linking neuronal identity, morphology and function in a Drosophila motion detection circuit.F32EY030025 · NEI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LOCASCIO, SAMUEL ALEXANDER · 2019 to 2020
$100k
NEI NIH HHS F32 EY030025NINDS NIH HHS T32 NS048004NINDS NIH HHS T32NS048004
6 · The paper itself

Abstract

Patterns of synaptic connectivity are remarkably precise and complex. Single-cell RNA sequencing has revealed a vast transcriptional diversity of neurons. Nevertheless, a clear logic underlying the transcriptional control of neuronal connectivity has yet to emerge. Here, we focused on

Indexed as

Neural ConductionTranscription, GeneticAnimalsAxonsCells, CulturedDendritesDrosophilaGene Expression RegulationSingle-Cell AnalysisD. melanogastergeneticsgenomicsneuronal connectivityneurosciencesingle-cell sequencingtranscriptional programs

Identifiers

PMID31687928
PMCPMC6855804

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.