Evidence map›Paper›PMID 31687869›Full record

ArticleHuman vaccines & immunotherapeutics2020

Age-stratified analysis of serotype-specific baseline immunity against group B streptococcus.

Min Joo Choi, Ji Yun Noh, A-Yeung Jang, Hee Jin Cheong, Woo Joo Kim, Dae Jin Song, Geum Joon Cho, Min Jeong Oh, Yong Zhi, Ho Seong Seo and 1 more

Abstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Min Joo ChoiDepartment of Internal Medicine, International St. Mary's Hospital, Catholic Kwandong University College of Medicine , Incheon, Korea.
Ji Yun NohDepartment of Internal Medicine, Korea University College of Medicine , Seoul, Republic of Korea.
A-Yeung JangDepartment of Internal Medicine, Korea University College of Medicine , Seoul, Republic of Korea.
Hee Jin CheongDepartment of Internal Medicine, Korea University College of Medicine , Seoul, Republic of Korea.ORCID 0000-0002-2532-1463
Woo Joo KimDepartment of Internal Medicine, Korea University College of Medicine , Seoul, Republic of Korea.
Dae Jin SongDepartment of Pediatrics, Korea University College of Medicine , Seoul, Republic of Korea.
Geum Joon ChoDepartment of Obstetrics and Gynecology, Korea University College of Medicine , Seoul, Republic of Korea.
Min Jeong OhDepartment of Obstetrics and Gynecology, Korea University College of Medicine , Seoul, Republic of Korea.
Yong ZhiBiotechnology Division, Korea Atomic Energy Research Institute , Jeongeup, Republic of Korea.ORCID 0000-0002-6970-3076
Ho Seong SeoBiotechnology Division, Korea Atomic Energy Research Institute , Jeongeup, Republic of Korea.ORCID 0000-0002-7103-1344
Joon Young SongDepartment of Internal Medicine, Korea University College of Medicine , Seoul, Republic of Korea.ORCID 0000-0002-0148-7194

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Group B streptococcus (GBS) vaccines are currently under development. Data on the natural immunity in diverse age groups will aid establishing the GBS immunization policy. In this study, thirty serum samples were collected from three age groups (neonates/infants, pregnant women, and the elderly) between August 2016 and July 2017. Serotype-specific opsonophagocytic activity (OPA) was assessed using a GBS multiplex opsonophagocytic killing assay (MOPA) against serotypes Ia, III, and V. The mean OPA titers for serotype Ia of the three age groups were not significantly different (

Indexed as

Streptococcal InfectionsAgedAntibodies, BacterialFemaleHumansInfantInfant, NewbornPlacentaPregnancySerogroupStreptococcus agalactiaeAntibodies, BacterialGBSgroup B streptococcusimmunityimmunoassayopsonophagocytic killing assayStreptococcus agalactiae

Identifiers

PMID31687869
PMCPMC7482737

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.