Evidence map›Paper›PMID 31687491›Full record

ArticleHeliyon2019

Characterization of functionalized multiwalled carbon nanotubes and comparison of their cellular toxicity between HEK 293 cells and zebra fish in vivo.

Ayush Chowdhry, Jasreen Kaur, Madhu Khatri, Veena Puri, Rakesh Tuli, Sanjeev Puri

Abstract read
In one paragraph

Article in Heliyon, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Review
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  5. Article
  6. Review
  7. Curcumin coating: a novel solution to mitigate inherent carbon nanotube toxicity.Journal of materials science. Materials in medicine · 2024
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Carbon Nanotubes: Smart Drug/Gene Delivery Carriers.International journal of nanomedicine · 2021
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ayush ChowdhryUniversity Institute of Engineering and Technology, Panjab University, Chandigarh, 160014, India.
Jasreen KaurUniversity Institute of Engineering and Technology, Panjab University, Chandigarh, 160014, India.
Madhu KhatriUniversity Institute of Engineering and Technology, Panjab University, Chandigarh, 160014, India.
Veena PuriCentre for Systems Biology and Bioinformatics, Panjab University, Chandigarh, 160014, India.
Rakesh TuliUniversity Institute of Engineering and Technology, Panjab University, Chandigarh, 160014, India.
Sanjeev PuriUniversity Institute of Engineering and Technology, Panjab University, Chandigarh, 160014, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbon nanotubes (CNTs) hold tremendous potential due to their unique and modifiable properties. Their robust biological applications necessitate minimizing their cytotoxicity and increasing the solubilization. In the present manuscript, we have functionalized multiwalled carbon nanotubes (MWCNTs) using defect functionalization methodology to covalently bind carboxy and amino groups on their walls. This functionalization was reassured through fourier-transform infrared spectroscopy (FTIR), energy dispersive x-ray analysis (EDX), elemental and field emission scanning electron microscopy (FE-SEM) analysis. The observations demonstrated that addition of carboxy as well as amino groups on MWCNTs, besides enabling MWCNTs solubilization also significantly ameliorated the cytotoxicity and the oxidative stress in comparison to pristine MWCNTs. It is envisaged that changes in agglomeration of the functionalized MWCNTs and the acquired surface charge is the reason for the reduction of cytotoxicity. Zebra fish embryo model test system employed for

Indexed as

Biological sciencesCarbon nanotubes (CNTs)ChemistryEnvironmental scienceFunctionalized MWCNTsMaterials scienceMulti walled carbon nanotubes (MWCNTs)MWCNT cytotoxicity

Identifiers

PMID31687491
PMCPMC6820100

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.