Evidence map›Paper›PMID 31687479›Full record

ArticleHeliyon2019

The potential of dendrimer in delivery of therapeutics for dentistry.

Ranjeet A Bapat, Suyog Dharmadhikari, Tanay V Chaubal, Mohd Cairul Iqbal Mohd Amin, Prachi Bapat, Bapi Gorain, Hira Choudhury, Christopher Vincent, Prashant Kesharwani

Abstract read
In one paragraph

Article in Heliyon, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
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  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Nanotechnology-based approaches applied to nutraceuticals.Drug delivery and translational research · 2022
    Review
  13. Article
  14. Biomineralization of Collagen-Based Materials for Hard Tissue Repair.International journal of molecular sciences · 2021
    Review
  15. Biocompatible and Biomaterials Application in Drug Delivery System in Oral Cavity.Evidence-based complementary and alternative medicine : eCAM · 2021
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ranjeet A BapatDivision of Clinical Dentistry, School of Dentistry, International Medical University, Kuala Lumpur, 57000, Malaysia.
Suyog DharmadhikariSchool of Dentistry, DY Patil University, Navi Mumbai, 400706, India.
Tanay V ChaubalDivision of Clinical Dentistry, School of Dentistry, International Medical University, Kuala Lumpur, 57000, Malaysia.
Mohd Cairul Iqbal Mohd AminCentre for Drug Delivery Research, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia.
Prachi BapatModern Dental College, Indore, 453112, Madhya Pradesh, India.
Bapi GorainSchool of Pharmacy, Faculty of Health and Medical Science, Taylor's University, Subang Jaya, 47500, Selangor, Malaysia.
Hira ChoudhurySchool of Pharmacy, Department of Pharmaceutical Technology, International Medical University, 57000, Kuala Lumpur, Malaysia.
Christopher VincentDivision of Oral Diagnostic and Surgical Sciences, School of Dentistry, International Medical University, Kuala Lumpur, 57000, Malaysia.
Prashant KesharwaniDepartment of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, 110062, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dendrimers are hyperbranched nanoparticle structures along with its surface modifications can to be used in dental biomaterials for biomimetic remineralisation of enamel and dentin. The review highlights the therapeutic applications of dendrimers in the field of dentistry. It addresses the possible mechanisms of enhancement of mechanical properties of adhesives and resins structure. Dendrimers due to its unique construction of possessing inner hydrophobic and outer hydrophilic structure can act as drug carrier for delivery of antimicrobial drugs for treatment of periodontal diseases and at peripheral dental implant areas. Dendrimers due to its hyperbranched structures can provides a unique drug delivery vehicle for delivery of a drug at specific site for sustained release for therapeutic effects. Thus, dendrimers can be one of the most important constituents which can be incorporated in dental biomaterials for better outcomes in dentistry.

Indexed as

AdhesivesAntimicrobialBiomimeticDendrimersDental plaqueDentistryMaterials sciencePeriodontal

Identifiers

PMID31687479
PMCPMC6820096

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.