Evidence map›Paper›PMID 31687431›Full record

ArticleData in brief2019

Statistical modelling of data showing pandemic H1N1 2009 swine influenza a virus infection kinetics in vaccinated pigs.

Laetitia Canini, Helen E Everett, Mario Aramouni, Vivien Coward, Andrew Ramsay, Michael Kelly, Sophie Morgan, Elma Tchilian, Sarah Gilbert, Bryan Charleston and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Data in brief, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Laetitia CaniniUniversity of Edinburgh, University of Edinburgh, Charlotte Auerbach Road, Edinburgh, EH9 3FL, UK.
Helen E EverettVirology Department, Animal and Plant Health Agency (APHA-Weybridge), New Haw, Addlestone, KT15 3NB, UK.
Mario AramouniThe Jenner Institute, University of Oxford, ORCRB, Roosevelt Drive, Oxford, OX3 7DQ, UK.
Vivien CowardVirology Department, Animal and Plant Health Agency (APHA-Weybridge), New Haw, Addlestone, KT15 3NB, UK.
Andrew RamsayVirology Department, Animal and Plant Health Agency (APHA-Weybridge), New Haw, Addlestone, KT15 3NB, UK.
Michael KellyVirology Department, Animal and Plant Health Agency (APHA-Weybridge), New Haw, Addlestone, KT15 3NB, UK.
Sophie MorganThe Pirbright Institute, Ash Road, Pirbright, Woking, GU24 0NF, UK.
Elma TchilianThe Pirbright Institute, Ash Road, Pirbright, Woking, GU24 0NF, UK.
Sarah GilbertThe Jenner Institute, University of Oxford, ORCRB, Roosevelt Drive, Oxford, OX3 7DQ, UK.
Bryan CharlestonThe Pirbright Institute, Ash Road, Pirbright, Woking, GU24 0NF, UK.
Ian H BrownVirology Department, Animal and Plant Health Agency (APHA-Weybridge), New Haw, Addlestone, KT15 3NB, UK.
Sharon M BrookesVirology Department, Animal and Plant Health Agency (APHA-Weybridge), New Haw, Addlestone, KT15 3NB, UK.
Mark E J WoolhouseUniversity of Edinburgh, University of Edinburgh, Charlotte Auerbach Road, Edinburgh, EH9 3FL, UK.

Funding

Biotechnology and Biological Sciences Research Council BB/L001330/1
6 · The paper itself

Abstract

A swine influenza A pandemic 2009 H1N1 (pH1N1) virus was used in a pig challenge model to investigate the efficacy of whole inactivated vaccines homologous or heterologous to the challenge virus as well as a commercial vaccine. Nasal shedding of viral RNA was monitored daily by real-time, quantitative RT-PCR (RRT-qPCR) as detailed (1). Here we report the statistical modelling of the viral RNA shedding kinetics.

Indexed as

Pandemic 2009 swine influenza a virusStatistical modelling RRT-qPCRViral kineticsWhole inactivated vaccine

Identifiers

PMID31687431
PMCPMC6820103

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.