ArticleERJ open research2019
Pregnancy after lung and heart-lung transplantation: a French multicentre retrospective study of 39 pregnancies.
Article in ERJ open research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Thoracic organ transplantation and pregnancy outcomes: systematic review and meta-analysis.Archives of gynecology and obstetrics · 2024Pooled it
- Outcomes and management strategies of pregnancies after heart and lung transplantation across Europe.JHLT open · 2026Article
- Planning a pregnancy after lung transplantation: Issues and considerations.Obstetric medicine · 2025Article
- Observational
- Pregnancy After Solid Organ Transplantation: Review of the Evidence and Recommendations.Transplantation · 2025Review
- Pregnancy outcomes and management in lung and heart transplant recipients: A systematic review.JHLT open · 2025Review
- Practice Patterns and Attitudes Regarding Pregnancy and Parenthood After Lung Transplantation.Transplantation direct · 2024Article
- Pregnancies and Gynecological Follow-Up after Solid Organ Transplantation: Experience of a Decade.Journal of clinical medicine · 2022Article
- Non-pulmonary complications after lung transplantation: part II.Indian journal of thoracic and cardiovascular surgery · 2022Review
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pregnancy after lung and heart-lung transplantation remains rare. This French study deals with change in lung function after a pregnancy and the maternal and newborn outcomes. We retrospectively included 39 pregnancies in 35 women aged >20 years. Data on patients, course of pregnancies and newborns were collected from nine transplantation centres. Mean age at time of pregnancy was 28 years. Cystic fibrosis affected 71% of patients. Mean±sd time between transplantation and pregnancy was 63±44 months. 26 births occurred (67%) with a mean term of 36 weeks of amenorrhoea and a mean birthweight of 2409 g. Prematurity was observed in 11 cases (43%). Forced expiratory volume in 1 s was 83.9% of predicted before pregnancy and 77.3% of predicted 1 year after the end of pregnancy (p=0.04). 10 patients developed chronic lung allograft dysfunction after delivery. Nine patients died at a mean±sd time after transplantation of 8.2±7 years and a mean±sd time after pregnancy of 4.6±6.5 years. These data show that pregnancy remains feasible in lung and heart-lung transplant recipients, with more frequent maternal and newborn complications than in the general population. Survival in this cohort appears to be similar to the global survival observed in lung transplant recipients. Planned pregnancy and multidisciplinary follow-up are crucial.
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Registered trials
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