ReviewAllergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology2019
The association between caesarean section and childhood asthma: an updated systematic review and meta-analysis.
Review in Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Effect of cesarean section on the risk of autism spectrum disorders/attention deficit hyperactivity disorder in offspring: a meta-analysis.Archives of gynecology and obstetrics · 2024Pooled it
- Association of cesarean section with asthma in children/adolescents: a systematic review and meta-analysis based on cohort studies.BMC pediatrics · 2023Pooled it
- Cesarean section and the risk of allergic rhinitis in children: a systematic review and meta-analysis.Scientific reports · 2023Pooled it
- Pediatrics Consequences of Caesarean Section-A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2020Pooled it
- Maternal and infant gut microbiome.iMeta · 2026Review
- The Acari Hypothesis, VIII: the human apocrine-mammary-microbiota axis andFrontiers in microbiology · 2026Article
- Early life gut microbiome and its impact on childhood health and chronic conditions.Gut microbes · 2025Review
- Consequences of host-microbiome interactions in preterm infants.Infection and immunity · 2025Review
- Risk factors for asthma across India: Results from global asthma network (GAN) phase I study.Lung India : official organ of Indian Chest Society · 2025Article
- Prenatal Maternal Stress and Pediatric Asthma Across Development: Adolescent Female-Specific Vulnerability.Child psychiatry and human development · 2025Article
- Association between cesarean delivery and childhood allergic diseases in a longitudinal population-based birth cohort from Japan.Scientific reports · 2025Article
- Health outcomes up to 5 years in children born as a second child after a previous caesarean section in a first pregnancy: a Swedish population-based register study between 1999 and 2015.BMJ paediatrics open · 2025Article
- Assessment of maternal health and behavior during pregnancy in the HEALthy Brain and Child Development Study: Rationale and approach.Developmental cognitive neuroscience · 2025Article
- Risk Factors Associated With Pediatric Asthma Hospitalization: A Retrospective Case-Control Study.Journal of family & reproductive health · 2024Article
- Early-life gut microbiota assembly patterns are conserved between laboratory and wild mice.Communications biology · 2024Article
- Asthma Inception: Epidemiologic Risk Factors and Natural History Across the Life Course.American journal of respiratory and critical care medicine · 2024Review
- Nonelective cesarean section is associated with the prevalence of asthma among Mexican children who attended childcare centers.Asia Pacific allergy · 2024Article
- Evaluation of Childhood Allergy Risk Among Pregnant Women in a Tertiary Care Hospital in Thailand.Cureus · 2024Article
- RETRACTED: Effect ofMicroorganisms · 2024Article
- Unraveling the Microbiome-Human Body Axis: A Comprehensive Examination of Therapeutic Strategies, Interactions and Implications.International journal of molecular sciences · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInvestigating the association between caesarean section (SC) and childhood asthma has shown contradictory results in different studies. The present study was conducted to determine the association between SC and childhood asthma. MATERIAL AND
methodThe present study was conducted based on the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines. All the steps of the study were conducted independently by two reviewers from the inception until February 1, 2019. In case of disagreement, the third reviewer resolved it. We searched international online databases, including Scopus, Cochrane Library, PubMed/Medline, Embase, Web of Science (ISI), Science Direct, and Google scholar. The results of studies were combined using random effects model, and heterogeneity was measured through I
resultsThe heterogeneity rate was high (I
conclusionAccording to the meta-analysis, SC (overall, elective, and emergency) increased the risk of childhood asthma. Therefore, it is hoped that developing clinical guidelines and implementing appropriate management plans would diminish the risk of asthma.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.