Evidence map›Paper›PMID 31687010›Full record

ArticleDermatology research and practice2019

Assessment of Serum Vitamin D Levels in Patients with Vitiligo in Jordan: A Case-Control Study.

Diala M Alshiyab, Firas A Al-Qarqaz, Leen H Heis, Jihan M Muhaidat, Wlla S Eddin, Ausama A Atwan

Open access · goldAbstract read
In one paragraph

Article in Dermatology research and practice, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. How Does Vitamin D Affect Immune Cells Crosstalk in Autoimmune Diseases?International journal of molecular sciences · 2023
    Review
  3. Article
  4. Article
  5. Article
  6. Osteoporosis in Skin Diseases.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Diala M AlshiyabDepartment of Dermatology, Faculty of Medicine, Jordan University of Science and Technology, Jordan.ORCID https://orcid.org/0000-0003-0244-0221
Firas A Al-QarqazDepartment of Dermatology, Faculty of Medicine, Jordan University of Science and Technology, Jordan.ORCID https://orcid.org/0000-0003-4876-7406
Leen H HeisDepartment of Dermatology, Faculty of Medicine, Jordan University of Science and Technology, Jordan.
Jihan M MuhaidatDepartment of Dermatology, Faculty of Medicine, Jordan University of Science and Technology, Jordan.
Wlla S EddinDepartment of Dermatology, Faculty of Medicine, Jordan University of Science and Technology, Jordan.
Ausama A AtwanDepartment of Dermatology, Royal Gwent Hospital, Newport, UK.
Jordan University of Science and Technology · JORoyal Gwent Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLow vitamin D serum levels have been associated with many autoimmune disorders and several other skin diseases. Vitiligo is an autoimmune disease characterized by destruction of melanocytes by immune mechanisms. Melanocytes express vitamin D receptors, and their function can be affected by vitamin D status.

objectivesThe main objective of this study is to compare vitamin D levels in patients with vitiligo vs normal population and whether vitamin D deficiency is associated with vitiligo.

methodsA case-control study was conducted. 100 vitiligo patients and 100 as controls were included in this study. Serum vitamin D level was measured for both vitiligo patients and controls, results were compared, and statistical analysis was done to compare the results.

resultsThe median age of vitiligo cases was 23 years (ranges, 2-80). 58% of vitiligo patients were females. The median vitamin D level was not significantly different between the two groups (vitiligo = 14.1 (IQR 9.9-20.4) vs control = 16.5 (IQR 10.3-25.3) (

conclusionsThere was no significant difference in vitamin D levels in vitiligo patients compared to controls. However, vitamin D levels were generally low in both groups.

Identifiers

PMID31687010
PMCPMC6811793
OpenAlexW2980105865

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.