Evidence map›Paper›PMID 31686917›Full record

ArticleClinical, cosmetic and investigational dentistry2019

Ion release of chitosan and nanodiamond modified glass ionomer restorative cements.

Riaan Mulder, Charney Anderson-Small

Registry-linked trialAbstract read
In one paragraph

Article in Clinical, cosmetic and investigational dentistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04365270 (The Antimicrobial Activity and Clinical Performance of Chitosan-modified Glass Ionomer), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04365270 phase3completednot on this map

The Antimicrobial Activity and Clinical Performance of Chitosan-modified Glass Ionomer: A Randomized Clinical Trial

TypeinterventionalSponsorAin Shams UniversityRan2019 to 2021Enrolled65ConditionsReversible Pulpitis, Pulpitis, Caries,Dental, Caries Class IArmsGlass Ionomer, Chitosan Low Molecular Weight (20-200 Mpa.S), Chlorhexidine Diacetate, Titanium Dioxide
3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. The applications of polysaccharides in dentistry.Frontiers in bioengineering and biotechnology · 2022
    Review
  8. Review
  9. Article
  10. Kinetics of ion release from a conventional glass-ionomer cement.Journal of materials science. Materials in medicine · 2021
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Riaan MulderPaediatric Dentistry, The University of the Western Cape, Cape Town, South Africa.ORCID 0000-0002-8722-7632
Charney Anderson-SmallCentral Analytical Facilities, Stellenbosch University, Cape Town, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIon release from glass ionomer restorative cements (GICs) plays an important role in GICs. The ion release from chitosan and nanodiamond-modified glass ionomers was assessed. MATERIALS AND

methodsThree GICs (Fuji IX, Ketac Universal and Riva Self Cure) were modified in the powder phase per weight by adding 5% or 10% of a commercially available chitosan powder (CH) or nanodiamond (ND) powder to the GICs. The specimens with dimensions 4 mm diameter and 6 mm height manufactured from the 15 GIC formulations were allowed to set for 1 hr and subsequently placed in neutral de-ionised water. The released ions were assessed using inductively coupled plasma-mass spectrometer (ICP-MS) to determine the elemental release. Additionally, three different disc-shaped specimens (3 mm in diameter and 1 mm thick) were constructed from each material for scanning electron microscopy (SEM) and energy dispersive X-ray spectrometry (SEM-EDS) microanalysis to establish an ion weight percentage.

resultsThere were no significant differences in the ion release between the control materials for aluminium, silicon and strontium. The ion release from CH and most ND-modified GICs were significantly (

conclusionIon release can be advantageous to tooth structure due to the interaction of chitosan with the GIC chemistry and moisture during maturation. Ion release up to five times greater than the control was noted for some ions.

Indexed as

aluminiumchitosanglass ionomer cementICP-MSnanodiamondstrontium

Identifiers

PMID31686917
PMCPMC6737163

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.