Evidence map›Paper›PMID 31686897›Full record

ArticleJournal of pain research2019

High cervical spinal cord stimulation for occipital neuralgia: a case series and literature review.

Pavlos Texakalidis, Muhibullah S Tora, Purva Nagarajan, Orion P Keifer, Nicholas M Boulis

Open access · goldAbstract read
In one paragraph

Article in Journal of pain research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Cervical Spinal Cord Stimulation: A Review.Current pain and headache reports · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Pavlos TexakalidisDepartment of Neurosurgery, Emory University School of Medicine, Atlanta, GA, USA.
Muhibullah S ToraDepartment of Neurosurgery, Emory University School of Medicine, Atlanta, GA, USA.
Purva NagarajanDepartment of Neurosurgery, Emory University School of Medicine, Atlanta, GA, USA.
Orion P KeiferDepartment of Neurosurgery, Emory University School of Medicine, Atlanta, GA, USA.
Nicholas M BoulisDepartment of Neurosurgery, Emory University School of Medicine, Atlanta, GA, USA.
Emory University · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM008169 · NIGMS · EMORY UNIVERSITY · PI GROSS, ROBERT E · 1987 to 2021
$20.3M
NIGMS NIH HHS T32 GM008169
6 · The paper itself

Abstract

backgroundOccipital neuralgia (ON) is defined as paroxysmal pain in the distribution of the greater, lesser, and/or third occipital nerves. ON can be refractory to conservative management and minimally invasive interventions. Neuromodulatory procedures can potentially treat refractory ON and include occipital nerve stimulation and the sparsely reported high cervical spinal cord stimulation (SCS).

objectiveTo report our experience and conduct a systematic literature review of studies evaluating the effect of high cervical SCS as a treatment modality for refractory ON.

methodsA retrospective review of patients with refractory ON who underwent high cervical SCS was conducted. In addition, a systematic literature review was performed according to the PRISMA guidelines.

resultsFive patients with refractory ON were treated with high cervical (C1-C3) SCS in our institution. Two out of five (40%) patients reported a successful trial stimulation (>50% pain reduction) and received permanent implantation. During the follow-up, the visual analog scale score decreased from 7.5 to 4 and from 6.5 to 5 in these patients. No complications were reported for any of the patients. The systematic literature review, identified two eligible studies, comprising 18 patients overall who underwent cervicomedullary junction SCS. Nine out of 18 patients (50%) had a successful trial and received permanent implantation.

conclusionHigh cervical or cervicomedullary junction SCS is associated with a 40-50% successful trial rate in refractory ON. No major complications were noted during the follow-up. Future studies are needed to compare the different neurosurgical options, in order to identify the optimal treatment strategy for refractory ON.

Indexed as

neuromodulationoccipital neuralgiaspinal cord stimulation

Identifiers

PMID31686897
PMCPMC6708893
OpenAlexW2969237706

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.