Evidence map›Paper›PMID 31686883›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2019

Lymphocyte To High-Density Lipoprotein Ratio As A New Indicator Of Inflammation And Metabolic Syndrome.

Haishan Chen, Chongxiang Xiong, Xiaofei Shao, Jing Ning, Peichun Gao, Hua Xiao, Yunying Chen, Ziliang Zou, Guobao Hong, Xiaolin Li and 5 more

Open access · goldAbstract read
In one paragraph

Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.

  1. Can biomarkers be used to improve diagnosis and prediction of metabolic syndrome in childhood cancer survivors? A systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021
    Pooled it
  2. Trial
  3. The association between high-density lipoprotein-related inflammation index and female infertility prevalence: Insight from a cross-sectional study of NHANES.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Haishan Chen *Department of Nephrology, The Third Affiliated Hospital, Southern Medical University, Guangzhou 510630, People's Republic of China.
Chongxiang XiongDepartment of Nephrology, The Third Affiliated Hospital, Southern Medical University, Guangzhou 510630, People's Republic of China.
Xiaofei Shao *Department of Nephrology, The Third Affiliated Hospital, Southern Medical University, Guangzhou 510630, People's Republic of China.
Jing NingDepartment of Nephrology, The Third Affiliated Hospital, Southern Medical University, Guangzhou 510630, People's Republic of China.
Peichun GaoDepartment of Nephrology, The Third Affiliated Hospital, Southern Medical University, Guangzhou 510630, People's Republic of China.
Hua XiaoDepartment of Nephrology, The Third Affiliated Hospital, Southern Medical University, Guangzhou 510630, People's Republic of China.
Yunying ChenDepartment of Nephrology, The Third Affiliated Hospital, Southern Medical University, Guangzhou 510630, People's Republic of China.
Ziliang ZouDepartment of Nephrology, The Third Affiliated Hospital, Southern Medical University, Guangzhou 510630, People's Republic of China.
Guobao HongDepartment of Nephrology, The Third Affiliated Hospital, Southern Medical University, Guangzhou 510630, People's Republic of China.
Xiaolin LiDepartment of Nephrology, The Third Affiliated Hospital, Southern Medical University, Guangzhou 510630, People's Republic of China.
Mengjiao ShaoDepartment of Nephrology, The Third Affiliated Hospital, Southern Medical University, Guangzhou 510630, People's Republic of China.
Jieli ShengDepartment of Nephrology, The Third Affiliated Hospital, Southern Medical University, Guangzhou 510630, People's Republic of China.
Xingyan YangDepartment of Nephrology, The Third Affiliated Hospital, Southern Medical University, Guangzhou 510630, People's Republic of China.
Xu YouDepartment of Nephrology, The Third Affiliated Hospital, Southern Medical University, Guangzhou 510630, People's Republic of China.
Hequn ZouDepartment of Nephrology, The Third Affiliated Hospital, Southern Medical University, Guangzhou 510630, People's Republic of China.
Third Affiliated Hospital of Southern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMetabolic syndrome (MetS), which is a global public health problem, is a state of chronic low-grade inflammation. This study looked at the changes in hematological parameters and the predictive value of the lymphocyte to high-density lipoprotein cholesterol (HDL-C) ratio (LHR) as a new index in subjects with and without MetS in coastal cities in southern China. PATIENTS AND

methodsIn this cross-sectional study, there were 852 participants (n = 598 with MetS and n = 254 without MetS). MetS was defined in accordance with the National Cholesterol Education Program, Adult Treatment Panel III (NCEP-ATP III) criteria.

resultsMetS was positively correlated with white blood cell count, total lymphocyte count, neutrophil count, red blood cell count, hematocrit, hemoglobin, and high-sensitivity C-reactive protein levels (

conclusionIn summary, MetS can involve changes in blood parameters, and LHR may be a useful marker of inflammation to assess the presence and severity of MetS.

Indexed as

inflammationlymphocyte to high-density lipoprotein cholesterol ratiomarkermetabolic syndrome

Identifiers

PMID31686883
PMCPMC6798814
OpenAlexW2979447618

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.