ArticleInternational journal of nanomedicine2019
Grafting of multiwalled carbon nanotubes with pyrazole derivatives: characterization, antimicrobial activity and molecular docking study.
Article in International journal of nanomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Synthesis, antibacterial evaluation and in silico studies of novel 2-(benzo[d]thiazol-2-yl)-N-arylacetamides and their derivatives as potential DHFR inhibitors.BMC chemistry · 2025Article
- Design, synthesis of some novel coumarins and their nanoformulations into lipid-chitosan nanocapsule as unique antimicrobial agents.Scientific reports · 2024Article
- Functionalization of MWCNTs for Bioelectrocatalysis by Bacterial Two-Domain Laccase fromNanomaterials (Basel, Switzerland) · 2023Article
- Synthesis and Biological Evaluation of Benzothiazolyl-pyridine Hybrids as New Antiviral Agents against H5N1 Bird Flu and SARS-COV-2 Viruses.ACS omega · 2023Article
- New Insights intoNanomaterials (Basel, Switzerland) · 2023Review
- Article
- Novel Thiopyrano[2,3-ACS omega · 2023Article
- Substituted Pyrazoles and Their Heteroannulated Analogs-Recent Syntheses and Biological Activities.Molecules (Basel, Switzerland) · 2021Review
- Article
- Antimicrobial and anti-adhesive properties of carbon nanotube-based surfaces for medical applications: a systematic review.iScience · 2021Review
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Authors and funding
3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
introductionIt is well known that the grafted multiwalled carbon nanotubes (MWCNTs) have antibacterial activity and lower cytotoxicity. Moreover, pyrazole derivatives have a broad spectrum of biological activity due to their fertile template for many medicinal drugs. On view of these findings we report herein the hybridization between MWCNTs and some pyrazole derivatives as antibacterial agents. MATERIALS AND
methodsPyrazole and pyrazolone derivatives were grafted onto the surface of carboxylated MWCNTs via the reaction of carboxylated MWCNTs and the diazonium salts of pyrazoles and pyrazolones using mixed acid treatment. The insertion of the pyrazole and pyrazolone moieties was characterized by Fourier transform infrared (FTIR) spectroscopy, energy dispersion spectroscopy, transmission electron microscopy, X-ray diffraction and thermogravimetric (TGA).
resultsThe results indicate that pyrazole and pyrazolone moieties successfully attached on carboxylated MWCNTs surface. The neat pyrazole and pyrazolone derivatives and their corresponding carbon nanotubes were tested against
conclusionThe surface of the carboxylated MWCNTs was successfully grafted with some pyrazole derivatives. The antibacterial activity was investigated for the newly synthesized compounds and indicated that the grafted MWCNTs have good antibacterial activity toward some pathogenic types of bacteria.
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