Evidence map›Paper›PMID 31686775›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2019

Corneal Ectasia Risk And Percentage Tissue Altered In Myopic Patients Presenting For Refractive Surgery.

Hon Shing Ong, Mohamed Farook, Benjamin Boon Chuan Tan, Geraint P Williams, Marcony R Santhiago, Jodhbir S Mehta

Open access · goldAbstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  6. The 25th Anniversary of Laser Vision Correction in the United States.Clinical ophthalmology (Auckland, N.Z.) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Hon Shing OngDepartment of Corneal and External Diseases, Singapore National Eye Centre, Singapore, Singapore.ORCID 0000-0001-5475-8712
Mohamed FarookDepartment of Corneal and External Diseases, Singapore National Eye Centre, Singapore, Singapore.ORCID 0000-0002-6072-1147
Benjamin Boon Chuan TanDepartment of Corneal and External Diseases, Singapore National Eye Centre, Singapore, Singapore.ORCID 0000-0002-2564-4393
Geraint P WilliamsDepartment of Corneal and External Diseases, Singapore National Eye Centre, Singapore, Singapore.
Marcony R SanthiagoDepartment of Ophthalmology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Jodhbir S MehtaDepartment of Corneal and External Diseases, Singapore National Eye Centre, Singapore, Singapore.
Singapore National Eye Center · SGNanyang Technological University · SGUniversidade Federal do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeA percentage tissue altered (PTA) score of ≥40% has been advocated as an independent indicator of post-operative ectasia risk following laser in-situ keratomileusis (LASIK). This study was performed to test the hypothesis that refractive procedures, such as laser-assisted sub-epithelial keratectomy (LASEK) or small incision lenticule extraction (SMILE), may alter the range of PTA, within which refractive corneal surgery can be safely performed.

settingRefractive department, tertiary ophthalmic hospital.

designRetrospective observational study.

methodsReview of case notes was performed for patients who presented for refractive surgeries, other than LASIK. To determine the risk of corneal ectasia for each patient prior to refractive surgery, we estimated what each patient's PTA would have been if they had undergone LASIK. The Randleman Ectasia Risk Score System (ERSS) was also calculated.

results114 eyes (66 patients) were included. 94 eyes underwent SMILE. 20 eyes underwent LASEK. A significant proportion of eyes had PTA ≥40% - SMILE eyes: up to 31.9%, LASEK eyes: up to 60.0% (at presumed LASIK flap of 120 μm). The maximum calculated PTA was up to 47.9% in the SMILE group and up to 51.5% in the LASEK group. Using ERSS, 12.8-16% of SMILE eyes and 15.0-80.0% of LASEK eyes would have been considered to have moderate-to-high ectasia risk. No post-surgical ectasia was observed at 3 years.

conclusionSMILE and LASEK alter the range of PTA, within which corneal refractive surgery may be performed with a lower risk of developing post-operative corneal ectasia; a safe PTA threshold needs to be determined for these procedures before recommendations for clinical practice can be made.

Indexed as

ectasialaser-assisted sub-epithelial keratectomylaser in situ keratomileusispercentage tissue alteredrefractive surgerysmall incision lenticule extraction

Identifiers

PMID31686775
PMCPMC6798818
OpenAlexW2980012691

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.