Evidence map›Paper›PMID 31686724›Full record

ReviewIndian journal of clinical biochemistry : IJCB2019

Cadmium in Human Diseases: It's More than Just a Mere Metal.

Ghizal Fatima, Ammar Mehdi Raza, Najah Hadi, Nitu Nigam, Abbas Ali Mahdi

Open access · greenAbstract readReview
In one paragraph

Review in Indian journal of clinical biochemistry : IJCB, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 257 citations in OpenAlex.

  1. Article
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  15. Development of BaSrTiOScientific reports · 2025
    Article
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  18. Greywater Reuse: Contaminant Profile, Health Implications, and Sustainable Solutions.International journal of environmental research and public health · 2025
    Review
  19. Review
  20. Review

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Ghizal FatimaDepartment of Biotechnology, Era's Medical College and Hospital, Lucknow, India.ORCID 0000-0001-8516-655X
Ammar Mehdi RazaEra's Medical College and Hospital, Lucknow, India.
Najah Hadi3Department of Pharmacology, College of Medicine, Kufa University, Kufa, Iraq.
Nitu Nigam4Department of Cytogenetics, King George Medical University, Lucknow, India.
Abbas Ali Mahdi5Department of Biochemistry, King George Medical University, Lucknow, India.
Era's Lucknow Medical College and Hospital · INKing George's Medical University · INUniversity of Kufa · IQ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cadmium (Cd), poisoning has been reported from all around the World, causing many deaths annually. Cd is a toxic heavy metal, and is widely present in environment. It has been reported that chronic Cd exposure is associated with kidney disease, osteoporosis, cardiovascular diseases and cancer. Smoking causes exposure to significantly higher Cd levels in humans. Tobacco smoke transports Cd into the lungs. Blood then transport it to the rest of the body where it increases effects by potentiating Cd that is already present from Cd-rich food. Other high exposures of Cd can occur with people, who live near hazardous waste sites, or factories that release Cd into the air and people who work in the metal refinery industry. Breathing of Cd can severely damage the lungs and may even cause death. Multiple studies have shown an association between environmental exposure to hazardous chemicals including toxic metals and obesity, diabetes, and metabolic syndrome. At the same time, the existing data on the impact of Cd exposure on obesity and diabetes are contradictory. On the converse, results of epidemiologic studies linking Cd exposure and Osteoporosis, overweight or obesity are far less consistent and even conflicting, also depending on differences in exposure levels. In turn, laboratory studies demonstrated that Cd adversely affects adipose tissue physiopathology through several mechanisms, thus contributing to increased insulin resistance and enhancing diabetes. However, intimate biological mechanisms linking Cd exposure with human diseases are still to be adequately investigated. Therefore, the aim of the present review was to explore the impact of Cd exposure and status on the risk of Cd in human diseases.

Indexed as

CadmiumHuman diseasesToxicity

Identifiers

PMID31686724
PMCPMC6801231
OpenAlexW2955768734

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.