Evidence map›Paper›PMID 31686650›Full record

ArticleeLife2019

A single clonal lineage of transmissible cancer identified in two marine mussel species in South America and Europe.

Marisa A Yonemitsu, Rachael M Giersch, Maria Polo-Prieto, Maurine Hammel, Alexis Simon, Florencia Cremonte, Fernando T Avilés, Nicolás Merino-Véliz, Erika Av Burioli, Annette F Muttray and 9 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 91 citations in OpenAlex.

  1. Article
  2. Atlantic to Pacific: Outbreak of bivalve transmissible neoplasia detected in hybridizing soft-shell clams and eDNA in Puget Sound.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Harmonized nonhuman cancer database.bioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. Article
  7. Horizontal transfer of nuclear DNA in transmissible cancer.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. De novo evolution of transmissible tumours in hydra.Proceedings. Biological sciences · 2024
    Article
  12. Article
  13. Article
  14. TheViruses · 2024
    Article
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 8 institutions in 5 countries.

Marisa A YonemitsuPacific Northwest Research Institute, Seattle, United States.ORCID 0000-0003-3290-4306
Rachael M GierschPacific Northwest Research Institute, Seattle, United States.
Maria Polo-PrietoHoward Hughes Medical Institute, Chevy Chase, United States.
Maurine HammelISEM, Université de Montpellier, CNRS- EPHE-IRD, Montpellier, France.
Alexis SimonISEM, Université de Montpellier, CNRS- EPHE-IRD, Montpellier, France.ORCID 0000-0002-6176-5045
Florencia CremonteLaboratorio de Parasitología (LAPA), Instituto de Biología de Organismos Marinos (IBIOMAR) (CCT CONICET - CENPAT), Puerto Madryn, Argentina.
Fernando T AvilésInstituto de Ciencias Biomedicas, Facultad de Medicina y Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago, Chile.
Nicolás Merino-VélizInstituto de Ciencias Biomedicas, Facultad de Medicina y Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago, Chile.
Erika Av BurioliResearch and Development, LABÉO Frank Duncombe, Saint-Contest, France.
Annette F MuttrayEnvironmental Resources Management, Vancouver, Canada.
James SherryWater Science & Technology Directorate, Environment and Climate Change Canada, Burlington, Canada.
Carol ReinischWater Science & Technology Directorate, Environment and Climate Change Canada, Burlington, Canada.
Susan A BaldwinChemical and Biological Engineering, University of British Columbia, Vancouver, Canada.
Stephen P GoffHoward Hughes Medical Institute, Chevy Chase, United States.ORCID 0000-0002-9679-0582
Maryline HoussinResearch and Development, LABÉO Frank Duncombe, Saint-Contest, France.
Gloria ArriagadaInstituto de Ciencias Biomedicas, Facultad de Medicina y Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago, Chile.
Nuria VázquezLaboratorio de Parasitología (LAPA), Instituto de Biología de Organismos Marinos (IBIOMAR) (CCT CONICET - CENPAT), Puerto Madryn, Argentina.
Nicolas BierneISEM, Université de Montpellier, CNRS- EPHE-IRD, Montpellier, France.ORCID 0000-0003-1856-3197
Michael J MetzgerPacific Northwest Research Institute, Seattle, United States.ORCID 0000-0001-7855-1388
Centre National de la Recherche Scientifique · FRPacific Northwest Diabetes Research Institute · USUniversidad Andrés Bello · CLCentro Científico Tecnológico Patagónico · AREnvironment and Climate Change Canada · CAHoward Hughes Medical Institute · USLabéo · FRUniversity of British Columbia · CA

Funding

Evolution of transmissible cancers and genetics of host resistanceK22CA226047 · NCI · PACIFIC NORTHWEST RESEARCH INSTITUTE · PI METZGER, MICHAEL JEFFREY · 2018 to 2020
$579k
Agence Nationale de la Recherche ANR-18-CE35-0009Consejo Nacional de Investigaciones Científicas y Técnicas 2014-0670Fondo Nacional de Desarrollo Científico y Tecnológico FONDECYT1180705Howard Hughes Medical Institute EXROPHoward Hughes Medical Institute Goff LabMontpellier Université d'Excellence BLUECANCERNCI NIH HHS K22 CA226047NIH HHS K22 CA226047
6 · The paper itself

Abstract

Transmissible cancers, in which cancer cells themselves act as an infectious agent, have been identified in Tasmanian devils, dogs, and four bivalves. We investigated a disseminated neoplasia affecting geographically distant populations of two species of mussels (

Indexed as

Aquatic OrganismsMytilusAllelesAnimalsEuropeNeoplasmsPhylogenyPolymorphism, Single NucleotideSequence Analysis, DNASouth Americabivalvebivalve transmissible neoplasiacancer biologyinfectious diseasemicrobiologyMytilusMytilus chilensisMytilus edulistransmissible cancer

Identifiers

PMID31686650
PMCPMC6831032
OpenAlexW2988132553

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.