Evidence map›Paper›PMID 31686527›Full record

ArticleJournal of diabetes science and technology2020

Five-Year Two-Center Retrospective Comparison of Central Laboratory Glucose to GEM 4000 and ABL 800 Blood Glucose: Demonstrating the (In)adequacy of Blood Gas Glucose.

George Cembrowski, Joanna Jung, Junyi Mei, Eric Xu, Tihomir Curic, Rt Noel Gibney, Michael Jacka, Hossein Sadrzadeh

Open access · bronzeAbstract readComparative StudyMulticenter Study
In one paragraph

Article in Journal of diabetes science and technology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Accuracy of the Nova StatStripCanadian journal of anaesthesia = Journal canadien d'anesthesie · 2023
    Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

George CembrowskiLaboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada.ORCID 0000-0001-5957-2941
Joanna JungLaboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada.
Junyi MeiCollege of Medicine, University of Manitoba, Winnipeg, MB, Canada.
Eric XuCollege of Medicine, University of Manitoba, Winnipeg, MB, Canada.
Tihomir CuricCalgary Laboratory Services, AB, Canada.
Rt Noel GibneyCritical Care, School of Medicine, University of Alberta, Edmonton, AB, Canada.
Michael JackaCritical Care, School of Medicine, University of Alberta, Edmonton, AB, Canada.
Hossein SadrzadehCalgary Laboratory Services, AB, Canada.
University of Alberta · CAUniversity of Manitoba · CACalgary Laboratory Services · CAUniversity of Calgary · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the glucose assays of two blood gas analyzers (BGAs) in intensive care unit (ICU) patients by comparing ICU BGA glucoses to central laboratory (CL) glucoses of almost simultaneously drawn specimens.

methodsData repositories provided five years of ICU BGA glucoses and contemporaneously drawn CL glucoses from a Calgary, Alberta ICU equipped with IL GEM 4000 and CL Roche Cobas 8000-C702, and an Edmonton, Alberta ICU equipped with Radiometer ABL 800 and CL Beckman-Coulter DxC. Blood glucose analyzer and CL glucose differences were evaluated if they were both drawn either within ±15 or ±5 minutes. Glucose differences were assessed graphically and quantitatively with simple run charts and the surveillance error grid (SEG) and quantitatively with the 2016 Food and Drug Administration guidance document, with ISO 15197 and SEG statistical summaries. As the GEM glucose exhibits diurnal variation, CL-arterial blood gas (ABG) differences were evaluated according to time of day.

resultsCompared to the GEM glucoses measured between 0200 and 0800, the run charts of (GEM-CL) glucose demonstrate significant outliers between 0800 and 0200 which are identified as moderate to severe clinical outliers by SEG analysis ( DISCUSSION: The GEM ABG glucose is associated with a higher frequency of moderate to severe glucose clinical outliers, especially between 0800 and 0200, increased CL testing and higher average patient glucoses.

Indexed as

AlbertaBiomarkersBlood Gas AnalysisBlood GlucoseEquipment DesignHumansIntensive Care UnitsPredictive Value of TestsReproducibility of ResultsRetrospective StudiesBiomarkersBlood Glucoseblood gas analyzerGEM 4000glucose accuracyICURadiometer ABL 800surveillance error grid

Identifiers

PMID31686527
PMCPMC7576946
OpenAlexW2988405476

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.