Evidence map›Paper›PMID 31686409›Full record

ArticleJournal of nephrology2020

Lung ultrasound to detect and monitor pulmonary congestion in patients with acute kidney injury in nephrology wards: a pilot study.

Vincenzo Panuccio, Rocco Tripepi, Giovanna Parlongo, Angela Mafrica, Graziella Caridi, Francesco Catalano, Francesco Marino, Giovanni Tripepi, Francesca Mallamaci, Carmine Zoccali

Abstract read
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In one paragraph

Article in Journal of nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Vincenzo PanuccioNephrology, Dialysis and Transplantation Unit, Ospedali Riuniti, Reggio Calabria, Italy.
Rocco TripepiCNR-IFC, Clinical Epidemiology and Pathophysiology of Renal Diseases and Hypertension, Nefrologia-Ospedali Riuniti, 89100, Reggio Calabria, Italy.
Giovanna ParlongoNephrology, Dialysis and Transplantation Unit, Ospedali Riuniti, Reggio Calabria, Italy.
Angela MafricaCNR-IFC, Clinical Epidemiology and Pathophysiology of Renal Diseases and Hypertension, Nefrologia-Ospedali Riuniti, 89100, Reggio Calabria, Italy.
Graziella CaridiNephrology, Dialysis and Transplantation Unit, Ospedali Riuniti, Reggio Calabria, Italy.
Francesco CatalanoNephrology, Dialysis and Transplantation Unit, Ospedali Riuniti, Reggio Calabria, Italy.
Francesco MarinoNephrology, Dialysis and Transplantation Unit, Ospedali Riuniti, Reggio Calabria, Italy.
Giovanni TripepiNephrology, Dialysis and Transplantation Unit, Ospedali Riuniti, Reggio Calabria, Italy.
Francesca MallamaciNephrology, Dialysis and Transplantation Unit, Ospedali Riuniti, Reggio Calabria, Italy.
Carmine ZoccaliCNR-IFC, Clinical Epidemiology and Pathophysiology of Renal Diseases and Hypertension, Nefrologia-Ospedali Riuniti, 89100, Reggio Calabria, Italy. carmine.zoccali@tin.it.ORCID http://orcid.org/0000-0002-6616-1996
Ospedali Riuniti di Foggia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLung congestion and frank pulmonary edema are established complications of acute kidney injury (AKI) and early detection and monitoring of lung congestion may be useful for the clinical management of AKI patients.

methodsWe compared standardized clinical criteria (including lung crackles and peripheral edema grading) and simultaneous chest ultrasound (US) to detect lung congestion in a series of 39 inpatients with AKI.

resultsAt baseline, twelve patients (31%) were clinically euvolemic and twelve presented clear-cur cardiovascular congestion (31%) by clinical criteria. Fifteen patients (38%) were hypovolemic. The median number of US-B lines in patients with cardiovascular congestion was much higher (50, inter-quartile range 27-99) than in euvolemic (14, IQR 11-37) and hypovolemic patients (7, IQR 3-16, P < 0.001). Remarkably, a substantial proportion of asymptomatic euvolemic (66%) and hypovolemic (46%) patients had lung congestion of moderate to severe degree (> 15 US-B lines) by lung US. Crackles severity and the number of US-B lines over time were inter-related (Spearman's ρ = 0.38, P < 0.01) but the agreement (Cohen k statistics) between the two metrics was unsatisfactory. Forty-eight percent of patients had lung congestion of moderate to severe degree by lung US and this estimate by far exceeded that by clinical criteria (32%).

conclusionsThis pilot study shows that chest US has potential for the detection of lung congestion at a pre-clinical stage in AKI. The results of this pilot study form the basis for a clinical trial testing the usefulness of this technique for guiding lung congestion treatment in patients with AKI.

Indexed as

UltrasonographyAcute Kidney InjuryAgedAged, 80 and overFemaleHospitalizationHumansMaleMiddle AgedPilot ProjectsPulmonary EdemaReproducibility of ResultsAKICKDLung congestionLung ultrasound

Identifiers

PMID31686409
OpenAlexW2987655144

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.