Evidence map›Paper›PMID 31686254›Full record

ArticleNeurosurgical review2020

Inflammation promotes progression of thrombi in intracranial thrombotic aneurysms.

Hime Suzuki, Takeshi Mikami, Tomoaki Tamada, Ryo Ukai, Yukinori Akiyama, Akinori Yamamura, Kiyohiro Houkin, Nobuhiro Mikuni

Abstract read
PubMed Publisher
In one paragraph

Article in Neurosurgical review, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Hime SuzukiDepartment of Neurosurgery, Sapporo Medical University, Sapporo, Hokkaido, Japan.
Takeshi MikamiDepartment of Neurosurgery, Sapporo Medical University, Sapporo, Hokkaido, Japan. tmikami@sapmed.ac.jp.ORCID http://orcid.org/0000-0002-8608-1037
Tomoaki TamadaDepartment of Neurosurgery, Sapporo Medical University, Sapporo, Hokkaido, Japan.
Ryo UkaiDepartment of Neurosurgery, Sapporo Medical University, Sapporo, Hokkaido, Japan.
Yukinori AkiyamaDepartment of Neurosurgery, Sapporo Medical University, Sapporo, Hokkaido, Japan.
Akinori YamamuraDepartment of Neurosurgery, Sapporo Medical University, Sapporo, Hokkaido, Japan.
Kiyohiro HoukinDepartment of Neurosurgery, Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan.
Nobuhiro MikuniDepartment of Neurosurgery, Sapporo Medical University, Sapporo, Hokkaido, Japan.
Sapporo Medical University · JPHokkaido University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advances in the understanding of the pathogenesis of arteriosclerosis, abdominal aorta aneurysms and dissections, and carotid artery plaques have focused on chronic inflammation. In this study, we report that inflammatory changes of thrombi contribute to the enlargement and growth of giant intracranial thrombotic aneurysms. Surgical and postmortem samples were collected from 12 cases of large or giant intracranial thrombotic aneurysms diagnosed via pathological investigations. Degeneration of the aneurysmal wall and the infiltration of inflammatory cells in the thrombi were assessed. The number of blood cells and immunohistochemical stain-positive cells was enumerated, and the inflammation and neovascularization in the thrombi were assessed. In all cases, the appearance of inflammatory cells (CD68

Indexed as

AgedAntigens, CD34Blood Cell CountDisease ProgressionEncephalitisFemaleHumansImmunohistochemistryIntracranial AneurysmIntracranial ThrombosisLectins, C-TypeLeukocyte CountLymphocyte CountMacrophagesMaleMannose-Binding LectinsAntigens, CD34Lectins, C-TypeMannose-Binding LectinsMannose ReceptorReceptors, Cell SurfaceCerebral aneurysmInflammationThrombotic aneurysm

Identifiers

PMID31686254
OpenAlexW2987928736

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.