Evidence map›Paper›PMID 31686107›Full record

ArticleNucleic acids research2020

The ProteomeXchange consortium in 2020: enabling 'big data' approaches in proteomics.

Eric W Deutsch, Nuno Bandeira, Vagisha Sharma, Yasset Perez-Riverol, Jeremy J Carver, Deepti J Kundu, David García-Seisdedos, Andrew F Jarnuczak, Suresh Hewapathirana, Benjamin S Pullman and 11 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 472 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
472citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

472 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Article
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  14. Journal of ginseng research · 2026
    Review
  15. Article
  16. Dear-OMG: An Omics-General Compression Method for Genomics, Proteomics and Metabolomics Data.Interdisciplinary sciences, computational life sciences · 2026
    Article
  17. Article
  18. A Landscape Analysis of Human SUMOylation.Molecular & cellular proteomics : MCP · 2026
    Article
  19. Decoding the Heart Failure Peptidome.Circulation. Heart failure · 2026
    Article
  20. Article

412 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Eric W DeutschInstitute for Systems Biology, Seattle, WA 98109, USA.
Nuno BandeiraCenter for Computational Mass Spectrometry, University of California, San Diego (UCSD), La Jolla, CA 92093, USA.
Vagisha SharmaUniversity of Washington, Seattle, WA 98195, USA.
Yasset Perez-RiverolEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
Jeremy J CarverCenter for Computational Mass Spectrometry, University of California, San Diego (UCSD), La Jolla, CA 92093, USA.
Deepti J KunduEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
David García-SeisdedosEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
Andrew F JarnuczakEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
Suresh HewapathiranaEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
Benjamin S PullmanCenter for Computational Mass Spectrometry, University of California, San Diego (UCSD), La Jolla, CA 92093, USA.
Julie WertzCenter for Computational Mass Spectrometry, University of California, San Diego (UCSD), La Jolla, CA 92093, USA.
Zhi SunInstitute for Systems Biology, Seattle, WA 98109, USA.
Shin KawanoFaculty of Contemporary Society, Toyama University of International Studies, Toyama 930-1292, Japan.
Shujiro OkudaNiigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510, Japan.
Yu WatanabeNiigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510, Japan.
Henning HermjakobEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
Brendan MacLeanUniversity of Washington, Seattle, WA 98195, USA.
Michael J MacCossUniversity of Washington, Seattle, WA 98195, USA.
Yunping ZhuState Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Life Omics, Beijing 102206, China.
Yasushi IshihamaGraduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8501, Japan.
Juan A VizcaínoEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.

Funding

TrainingP41GM103533 · NIGMS · UNIVERSITY OF WASHINGTON · PI MACCOSS, MICHAEL · 2012 to 2021
$20.7M
Shortening the development cycle time of Trans Proteomic Pipeline tools with high performance computingR01GM087221 · NIGMS · INSTITUTE FOR SYSTEMS BIOLOGY · PI DEUTSCH, ERIC, MORITZ, ROBERT L · 2010 to 2021
$6.0M
Skyline Targeted Proteomics EnvironmentR01GM103551 · NIGMS · UNIVERSITY OF WASHINGTON · PI MACCOSS, MICHAEL · 2012 to 2020
$3.4M
Advancing data and metadata standards for proteomics mass spectraR24GM127667 · NIGMS · INSTITUTE FOR SYSTEMS BIOLOGY · PI DEUTSCH, ERIC · 2017 to 2019
$1.2M
NIGMS NIH HHS P41 GM103533NIGMS NIH HHS R01 GM087221NIGMS NIH HHS R01 GM103551NIGMS NIH HHS R24 GM127667Wellcome Trust
6 · The paper itself

Abstract

The ProteomeXchange (PX) consortium of proteomics resources (http://www.proteomexchange.org) has standardized data submission and dissemination of mass spectrometry proteomics data worldwide since 2012. In this paper, we describe the main developments since the previous update manuscript was published in Nucleic Acids Research in 2017. Since then, in addition to the four PX existing members at the time (PRIDE, PeptideAtlas including the PASSEL resource, MassIVE and jPOST), two new resources have joined PX: iProX (China) and Panorama Public (USA). We first describe the updated submission guidelines, now expanded to include six members. Next, with current data submission statistics, we demonstrate that the proteomics field is now actively embracing public open data policies. At the end of June 2019, more than 14 100 datasets had been submitted to PX resources since 2012, and from those, more than 9 500 in just the last three years. In parallel, an unprecedented increase of data re-use activities in the field, including 'big data' approaches, is enabling novel research and new data resources. At last, we also outline some of our future plans for the coming years.

Indexed as

Databases, ProteinBig DataComputational BiologyData MiningProteomicsSoftwareSoftware DesignWeb Browser

Identifiers

PMID31686107
PMCPMC7145525

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.