Evidence map›Paper›PMID 31686099›Full record

ArticleThe journal of prevention of Alzheimer's disease2019

Mediterranean-Dash Intervention for Neurodegenerative Delay (MIND) Diet Slows Cognitive Decline After Stroke.

L Cherian, Y Wang, K Fakuda, S Leurgans, N Aggarwal, M Morris

Registry-linked trialAbstract read
In one paragraph

Article in The journal of prevention of Alzheimer's disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04337255 (MIND Diet and Dementia Prevention in Ischemic Stroke Patients), which is not on this map. Cited by 67 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04337255 naactive not recruitingnot on this mapstarted 2021, after this paper: background citation

MIND Diet and Dementia Prevention in Ischemic Stroke Patients

TypeinterventionalSponsorRush University Medical CenterRan2021 to 2026Enrolled250ConditionsCognitive Decline, Dementia, Vascular, Alzheimer Disease, DementiaArmsBehavioral Dietary intervention ( MIND Diet), Behavioral Usual Care Diet Intervention
3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  12. The enigma of vascular dementia: current state and emerging perspectives.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
  13. Article
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  16. Article
  17. Vital nutrition: enhancing health in advanced Parkinson's disease with device-aided therapies.Journal of neural transmission (Vienna, Austria : 1996) · 2025
    Review
  18. Updates on vascular dementia.Stroke and vascular neurology · 2025
    Review
  19. Article
  20. Review

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

L CherianLaurel Cherian, Rush University Medical Center, Chicago, IL USA, laurel_j_cherian@rush.edu.
Y Wang
K Fakuda
S Leurgans
N Aggarwal
M Morris

Funding

EPIDEMIOLOGY OF NEURAL RESERVE AND NEUROBIOLOGY IN AGINGR01AG017917 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 2001 to 2023
$43.3M
Diet Patterns and Alzheimer Disease and Other DementiasR01AG054476 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI SCHNEIDER, JULIE A. · 2017 to 2021
$2.3M
NIA NIH HHS R01 AG017917NIA NIH HHS R01 AG054476
6 · The paper itself

Abstract

objectiveThis study sought to determine if the MIND diet (a hybrid of the Mediterranean and Dash diets, with modifications based on the science of nutrition and the brain), is effective in preventing cognitive decline after stroke.

designWe analyzed 106 participants of a community cohort study who had completed a diet assessment and two or more annual cognitive assessments and who also had a clinical history of stroke. Cognition in five cognitive domains was assessed using structured clinical evaluations that included a battery of 19 cognitive tests. MIND diet scores were computed using a valid food frequency questionnaire (FFQ). Dietary components of the MIND diet included whole grains, leafy greens and other vegetables, berries, beans, nuts, lean meats, fish, poultry, and olive oil and reduced consumption of cheese, butter, fried foods, and sweets. MIND diet scores were modeled in tertiles. The influence of baseline MIND score on change in a global cognitive function measure and in the five cognitive domains was assessed using linear mixed models adjusted for age and other potential confounders.

resultsWith adjustment for age, sex, education, APOE-ε4, caloric intake, smoking, and participation in cognitive and physical activities, the top vs lowest tertiles of MIND diet scores had a slower rate of global cognitive decline (β = .08; CI = 0.0074, 0.156) over an average of 5.9 years of follow-up.

conclusionsHigh adherence to the MIND diet was associated with a slower rate of cognitive decline after stroke.

Indexed as

Dietary Approaches To Stop HypertensionDiet, MediterraneanAgedAged, 80 and overCognitive DysfunctionDisease ProgressionFemaleHumansMaleStrokecognitive declinedietnutritionpreventionStroke

Identifiers

PMID31686099
PMCPMC7199507

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.