ArticleNature microbiology2020
Genetic basis for the cooperative bioactivation of plant lignans by Eggerthella lenta and other human gut bacteria.
Open access · greenAbstract read
In one paragraph
Article in Nature microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.
0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
67 citing papers in PubMed, 101 citations in OpenAlex.
- Enterolignan Production in a Flaxseed Intervention Study in Postmenopausal US Women of African Ancestry and European Ancestry.Nutrients · 2021Trial
- Effect of a Flaxseed Lignan Intervention on Circulating Bile Acids in a Placebo-Controlled Randomized, Crossover Trial.Nutrients · 2020Trial
- Article
- How Gut Microbes Transform Dietary Phytonutrients: Enzymatic Pathways and Human Metabolite Exposure.Molecules (Basel, Switzerland) · 2026Review
- Eggerthella lenta: metabolism, pathogenesis and therapeutic implications.Nature reviews. Microbiology · 2026Review
- Gut Microbial Metabotypes Shape Polyphenol Bioactivity: Toward Precision Nutrition Strategies for Human Health.Nutrients · 2026Review
- A Validated LC-MS/MS Method for Quantifying Phenolic Acids, Lignans, and Enterolignans from Human Fecal Samples.ACS nutrition science · 2026Article
- Article
- Article
- A widespread gut bacterial lineage distinguished by redox metabolism and phage defense.bioRxiv : the preprint server for biology · 2026Article
- Gut microbe-derivedProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Gut bacterialGut microbes reports · 2026Review
- Comprehensive profiling of gut microbiota in postmenopausal osteoporosis.Turkish journal of medical sciences · 2026Article
- Distinct classes of gut bacterial molybdenum-dependent enzymes produce urolithins.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- The presence and induction of regioselective dehydroxylases dictate urolithin metabolism by Enterocloster species.NPJ biofilms and microbiomes · 2025Article
- Elucidation of a bacterial pathway for catabolism of the β-β-linked dilignol pinoresinol.mBio · 2025Article
- Investigating zinc's role in mitigating blood lead levels' toxicity on gut microbiota diversity: NHANES 2007-2010.Toxicology letters · 2025Article
- Activity of GPCR-targeted drugs influenced by human gut microbiota metabolism.Nature chemistry · 2025Article
- Enantiocomplementary Gut Bacterial Enzymes Metabolize Dietary Polyphenols.Journal of the American Chemical Society · 2025Article
- Trends in extraction and purification methods of Lignans in plant-derived foods.Food chemistry: X · 2025Review
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 5 institutions in 1 country.
Elizabeth N BessDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0003-0349-0423
Jordan E BisanzDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-8649-1706
Fauna YarzaDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-2512-6182
Annamarie BustionDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-7380-3619
Barry E RichDepartment of Chemistry, University of California, Irvine, Irvine, CA, USA.
Xingnan LiUniversity of Hawaii Cancer Center, Honolulu, HI, USA.
Seiya KitamuraDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA.
Emily WaligurskiDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.
Qi Yan AngDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.
Diana L AlbaDiabetes Center, University of California San Francisco, San Francisco, CA, USA.
Peter SpanogiannopoulosDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.
Stephen NayfachUnited States Department of Energy Joint Genome Institute, Walnut Creek, CA, USA.
Suneil K KoliwadDiabetes Center, University of California San Francisco, San Francisco, CA, USA.
Dennis W WolanDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-9879-8353
Adrian A FrankeUniversity of Hawaii Cancer Center, Honolulu, HI, USA.
Peter J TurnbaughDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA. peter.turnbaugh@ucsf.edu.ORCID http://orcid.org/0000-0002-0888-2875
University of California, San Francisco · USScripps Research Institute · USUniversity of Hawaiʻi at Mānoa · USUnited States Department of Energy · USUniversity of California, Irvine · US
Funding
University of Hawaii Cancer Center CCSGP30CA071789 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI GERTRAUD MASKARINEC · 1996 to 2026
$56.2MZIDOVUDINE &LAMIVUDINE &NEVIRAPINE COMBINATION THERAPY IN HIV 1 INFM01RR001271 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KESSLER, DAVID A · 1985 to 2006
$22.7MUCSF Nutrition Obesity Research CenterP30DK098722 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHRISTIAN VAISSE · 2015 to 2026
$14.6MPredicting and preventing drug metabolism by the human gut microbiomeR01HL122593 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Peter James Turnbaugh · 2016 to 2026
$5.7M(PQ10) Harnessing the human gut microbiome to predict chemotherapy outcomesR21CA227232 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ATREYA, CHLOE E., TURNBAUGH, PETER JAMES · 2018 to 2019
$378kNCI NIH HHS P30 CA071789NCI NIH HHS R21 CA227232NCRR NIH HHS M01 RR001271NHLBI NIH HHS R01 HL122593NIDDK NIH HHS P30 DK098722
Abstract
Plant-derived lignans, consumed daily by most individuals, are thought to protect against cancer and other diseases
Indexed as
Gene Expression ProfilingActinobacteriaAnimalsBacterial ProteinsBiotransformationGastrointestinal MicrobiomeGenome, BacterialHumansLignansMetabolic Networks and PathwaysMiceMicrobial ConsortiaPhylogenySpecies SpecificityBacterial ProteinsLignans
Identifiers
What OpenQuestion holds
Textmetadata
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.