ArticleNature ecology & evolution2019
Promotion of protocell self-assembly from mixed amphiphiles at the origin of life.
Article in Nature ecology & evolution, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
63 citing papers in PubMed.
- Article
- Increasing the Compositional Heterogeneity of Single-Chain Amphiphile Membranes Supported by Coacervate Cores Alters Stability and Properties of the Hybrid Protocells.Langmuir : the ACS journal of surfaces and colloids · 2026Article
- Entropy-Driven Amino Acid-Based Coacervates with Enzyme-Free Metabolism and Prebiotic Robustness.Journal of the American Chemical Society · 2025Article
- How hard is it to encapsulate life? The general constraints on encapsulation.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Article
- Programmable Host-Guest Recognition for Shape-Shifting Supramolecular Nanostructure States.ACS nano · 2025Article
- Nanometric and Hydrophobic Green Rust Minerals upon Exposure to Amino Acids and Nickel as Prerequisites for a Primitive Chemiosmosis.Life (Basel, Switzerland) · 2025Article
- Primitive homochiral polyester formation driven by tartaric acid and calcium availability.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Chemiosmotic ATP synthesis by minimal protocells.Cell reports. Physical science · 2025Article
- Dilution-driven gel-sol-gel-sol transitions by the sequential evolution of surfactant micelles.Nature communications · 2025Article
- Exploring glycolytic enzymes in disease: potential biomarkers and therapeutic targets in neurodegeneration, cancer and parasitic infections.Open biology · 2025Review
- Concomitant formation of protocells and prebiotic compounds under a plausible early Earth atmosphere.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Protocells by spontaneous reaction of cysteine with short-chain thioesters.Nature chemistry · 2025Article
- Electricity in the Creation of Life.Reviews of physiology, biochemistry and pharmacology · 2025Review
- Chemically Driven Division of Protocells by Membrane Budding.Journal of the American Chemical Society · 2024Article
- The bubble theory: exploring the transition from first replicators to cells and viruses in a landscape-based scenario.Theory in biosciences = Theorie in den Biowissenschaften · 2024Article
- Could Life Have Started on Mars? Planetary Conditions That Assemble and Destroy Protocells.Life (Basel, Switzerland) · 2024Article
- Natural soda lakes provide compatible conditions for RNA and membrane function that could have enabled the origin of life.PNAS nexus · 2024Article
- RETRACTED ARTICLE: Generation of long-chain fatty acids by hydrogen-driven bicarbonate reduction in ancient alkaline hydrothermal vents.Communications earth & environment · 2024Article
- Cyclophospholipids Enable a Protocellular Life Cycle.ACS nano · 2023Article
- Formation of vesicular structures from fatty acids formed under simulated volcanic hydrothermal conditions.Scientific reports · 2023Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Vesicles formed from single-chain amphiphiles (SCAs) such as fatty acids probably played an important role in the origin of life. A major criticism of the hypothesis that life arose in an early ocean hydrothermal environment is that hot temperatures, large pH gradients, high salinity and abundant divalent cations should preclude vesicle formation. However, these arguments are based on model vesicles using 1-3 SCAs, even though Fischer-Tropsch-type synthesis under hydrothermal conditions produces a wide array of fatty acids and 1-alkanols, including abundant C
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.