ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019
Sensory- and Motor-Related Responses of Layer 1 Neurons in the Mouse Visual Cortex.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 30 citations in OpenAlex.
- Article
- Imaging spatial transcriptomics reveals molecular patterns underlying accumulation of p-Ser129 α-synuclein in a transgenic mouse model.NPJ Parkinson's disease · 2026Article
- Article
- Heterogeneity of Layer 1 Interneurons in the Mouse Medial Prefrontal Cortex.The Journal of comparative neurology · 2025Article
- Article
- Auditory cortex conveys non-topographic sound localization signals to visual cortex.Nature communications · 2024Article
- Triple dissociation of visual, auditory and motor processing in mouse primary visual cortex.Nature neuroscience · 2024Article
- Review
- How 'visual' is the visual cortex? The interactions between the visual cortex and other sensory, motivational and motor systems as enabling factors for visual perception.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
- Sound Improves Neuronal Encoding of Visual Stimuli in Mouse Primary Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Transient Coupling between Infragranular and Subplate Layers to Layer 1 Neurons Before Ear Opening and throughout the Critical Period Depends on Peripheral Activity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Response Selectivity of the Lateral Posterior Nucleus Axons Projecting to the Mouse Primary Visual Cortex.Frontiers in neural circuits · 2022Article
- Bottom-up inputs are required for establishment of top-down connectivity onto cortical layer 1 neurogliaform cells.Neuron · 2021Article
- Cortical and Subcortical Circuits for Cross-Modal Plasticity Induced by Loss of Vision.Frontiers in neural circuits · 2021Article
- Mining the jewels of the cortex's crowning mystery.Current opinion in neurobiology · 2020Review
- Article
- Neural mechanisms underlying visual and auditory processing impairments in schizophrenia: insight into the etiology and implications for tailoring preventive and therapeutic interventions.American journal of translational research · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Cortical layer 1 (L1) contains a sparse and molecularly distinct population of inhibitory interneurons. Their location makes them ideally suited for affecting computations involving long-range corticocortical and subcortical inputs, yet their response properties remain largely unexplored. Here we attempt to characterize some of the functional properties of these neurons in the primary visual cortex of awake mice. We find that the strongest driver of L1 neuron activity is locomotion, with at least half of L1 neurons displaying locomotion-related activity. Visual responses are present in a similar fraction of neurons, but these responses are weaker and frequently suppressive. We also find that ∼43% of L1 neurons respond to noise stimuli and at least 14% respond to whisker touch, with these two populations being statistically independent. Finally, we find that 45% of L1 neurons have generally weak responses correlated with whisking activity. Overall, the spatial distributions of modality-specific responses were more or less random. Our work helps to establish the basic sensory- and motor-related responses of L1 interneurons, revealing several previously unreported characteristics.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.