Evidence map›Paper›PMID 31685586›Full record

Trial reportTobacco control2020

Evaluating the effect of switching to non-menthol cigarettes among current menthol smokers: an empirical study of a potential ban of characterising menthol flavour in cigarettes.

Krysten W Bold, Peter Jatlow, Lisa M Fucito, Tore Eid, Suchitra Krishnan-Sarin, Stephanie O'Malley

Registry-linked trialOpen access · greenAbstract readClinical Trial
In one paragraph

Trial report in Tobacco control, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03075839 (Impact of Switching to Non-Menthol Cigarettes Among Smokers), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03075839 nacompletednot on this map

Impact of Switching to Non-Menthol Cigarettes Among Smokers

TypeinterventionalSponsorYale UniversityRan2017 to 2018Enrolled33ConditionsTobacco UseArmsCigarette Brand Switching
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. The Impact of Menthol Cigarette Bans: A Systematic Review and Meta-Analysis.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Pooled it
  2. Trial
  3. Trial
  4. Manipulation of Menthol and Nicotine Content in Cigarettes: Effects on Smoking Behavior and Toxicant Exposure in Women Menthol Smokers.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023
    Trial
  5. Effect on Tobacco Use and Subjective Measures of Including E-cigarettes in a Simulated Ban of Menthol in Combustible Cigarettes.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2022
    Trial
  6. Effects on Smoking Behavior of Switching Menthol Smokers to Non-menthol Cigarettes.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2021
    Trial
  7. Trial
  8. Article
  9. The Relative Reinforcing Value of Menthol Among Young Adult Cigarette Smokers: Results From a Behavioral Choice Task.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. How Smokers of Menthol Cigarettes and Flavored Cigars Might Respond to FDA's Proposed Bans.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2022
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Krysten W BoldPsychiatry, Yale University School of Medicine, New Haven, Connecticut, USA krysten.bold@yale.edu.ORCID 0000-0002-8012-6118
Peter JatlowPsychiatry, Yale University School of Medicine, New Haven, Connecticut, USA.
Lisa M FucitoPsychiatry, Yale University School of Medicine, New Haven, Connecticut, USA.
Tore EidLaboratory Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
Suchitra Krishnan-SarinPsychiatry, Yale University School of Medicine, New Haven, Connecticut, USA.
Stephanie O'MalleyPsychiatry, Yale University School of Medicine, New Haven, Connecticut, USA.
Yale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale Center for the Study of Tobacco Product Use and Addiction (YCSTP) Project 2: Addictive Threshold of Nicotine and the Impact of SweetenersU54DA036151 · NIDA · YALE UNIVERSITY · PI LISA M FUCITO · 2018 to 2026
$41.6M
Yale Tobacco Center of Regulatory ScienceP50DA036151 · NIDA · YALE UNIVERSITY · PI KRISHNAN-SARIN, SUCHITRA, O'MALLEY, STEPHANIE S · 2013 to 2017
$20.6M
SUBSTANCE ABUSEK12DA000167 · NIDA · YALE UNIVERSITY · PI STEPHANIE S O'MALLEY, Marc N Potenza · 1991 to 2026
$17.7M
NCATS NIH HHS UL1 TR001863NIDA NIH HHS K12 DA000167NIDA NIH HHS P50 DA036151NIDA NIH HHS U54 DA036151
6 · The paper itself

Abstract

introductionMenthol cigarette use remains a serious public health problem, prompting the consideration of tobacco regulatory efforts to ban menthol cigarettes. The current study uses a novel empirical design to model the potential effects of a ban of menthol cigarettes on smoking behaviour among current menthol smokers.

methods29 non-treatment-seeking adults who smoked menthol cigarettes were recruited in Connecticut in 2017-2018 (n=15 female; n=17 Black, n=10 White, n=5 Hispanic). Repeated-measures analyses examined within-person changes in smoking behaviour when participants were switched from smoking their usual brand menthol cigarettes to a matched-brand non-menthol cigarette for 2 weeks to model a potential ban of menthol cigarettes.

resultsParticipants smoked significantly fewer non-menthol (vs menthol) cigarettes per day (mean decrease=2.2 cigarettes, SD=3.2, p<0.001), confirmed by significant reductions in urine cotinine levels (p=0.013). After switching to non-menthol cigarettes, participants had significantly lower nicotine dependence scores (reduced by >18%, p<0.001) and greater increases in quitting motivation and confidence (rated 1-10) (motivation: mean increase=2.1, SD=2.8, p<0.001; confidence: mean increase=1.3, SD=3.3, p=0.04). Exploratory analyses indicated significant interactions by race (p=0.004); Black smokers had greater reductions in cigarettes per day (mean decrease=3.5 cigarettes, SD=2.8) versus non-Black smokers (mean decrease=0.2, SD=2.6).

conclusionsBanning menthol as a characterising flavour in cigarettes may decrease smoking and reduce the addictive potential of cigarettes among current smokers. Results provide additional support for tobacco regulatory policies banning menthol flavour in an effort to improve public health.

trial registrationNCT03075839.

Indexed as

Tobacco ProductsTobacco Use DisorderAdultFemaleHumansMentholSmokersSmokingMentholaddictiondisparitiespriority/special populationspublic policy

Identifiers

PMID31685586
PMCPMC7259442
OpenAlexW2987909693

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.