Evidence map›Paper›PMID 31685584›Full record

ReviewTobacco control2021

Nearly 20 000 e-liquids and 250 unique flavour descriptions: an overview of the Dutch market based on information from manufacturers.

Anne Havermans, Erna J Z Krüsemann, Jeroen Pennings, Kees de Graaf, Sanne Boesveldt, Reinskje Talhout

Abstract readReview
In one paragraph

Review in Tobacco control, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  5. Mapping the flavoring landscape: a comparative analysis of tobacco and related products.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
    Article
  6. Toxicity and Appeal of Flavoured E-Cigarettes and Flavour Ban Outcomes: A Narrative Review.International journal of environmental research and public health · 2026
    Review
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  17. Young users of electronic cigarettes exhibit reduced cardiorespiratory fitness.Journal of applied physiology (Bethesda, Md. : 1985) · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anne HavermansCentre for Health Protection, National Institute for Public Health and the Environment, Bilthoven, The Netherlands anne.havermans@rivm.nl.ORCID 0000-0003-2874-6560
Erna J Z KrüsemannCentre for Health Protection, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.ORCID 0000-0003-3552-8190
Jeroen PenningsCentre for Health Protection, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.
Kees de GraafDivision of Human Nutrition and Health, Wageningen University, Wageningen, The Netherlands.
Sanne BoesveldtDivision of Human Nutrition and Health, Wageningen University, Wageningen, The Netherlands.
Reinskje TalhoutCentre for Health Protection, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesFlavours increase attractiveness of electronic cigarettes and stimulate use among vulnerable groups such as non-smoking adolescents. It is important for regulators to monitor the market to gain insight in, and regulate the range of e-liquid flavours that is available to consumers. E-liquid manufacturers are required to report key product information to authorities in the European Member States in which they plan to market their products. This information was used to provide an overview of e-liquid flavour descriptions marketed in the Netherlands in 2017.

methodsTwo researchers classified 19 266 e-liquids into the 16 main categories of the e-liquid flavour wheel, based on information from four variables in the European Common Entry Gate system. Flavour descriptions were further specified in subcategories.

resultsFor 16 300 e-liquids (85%), sufficient information was available for classification. The categories containing the highest number of e-liquids were

conclusionsIn 2017, ~20 000 e-liquids were reported to be marketed in the Netherlands, in 245 unique flavour descriptions. The variety of marketed flavour descriptions reflects flavour preference of e-cigarette users as described in literature. Our systematic classification of e-liquids by flavour description provides a tool for organising the huge variety in market supply, serves as an example for other countries to generate similar overviews and can support regulators in developing flavour regulations.

Indexed as

Electronic Nicotine Delivery SystemsTobacco ProductsAdolescentFlavoring AgentsHumansSmokersTasteFlavoring Agentsconsumer appeale-cigarettese-liquid manufacturinge-liquidsflavor descriptionsmarketingtobacco product directive

Identifiers

PMID31685584
PMCPMC7803909

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.