Evidence map›Paper›PMID 31685559›Full record

Trial reportCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2020

Psychotropic Medication Use and Postmenopausal Breast Cancer Risk.

Anna George, Susan R Sturgeon, Susan E Hankinson, Aladdin H Shadyab, Robert B Wallace, Katherine W Reeves

Open access · greenAbstract readClinical TrialMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 6 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 6 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  5. Pooled it
  6. Pooled it
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Observational
  13. Review
  14. Risk of Breast Cancer in Association with the Use of Second-generation Antipsychotics.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2022
    Article
  15. Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Anna GeorgeDepartment of Biostatistics and Epidemiology, University of Massachusetts Amherst, Amherst, Massachusetts.ORCID 0000-0002-0226-3854
Susan R SturgeonDepartment of Biostatistics and Epidemiology, University of Massachusetts Amherst, Amherst, Massachusetts.
Susan E HankinsonDepartment of Biostatistics and Epidemiology, University of Massachusetts Amherst, Amherst, Massachusetts.
Aladdin H ShadyabDepartment of Family Medicine and Public Health, University of California, San Diego, La Jolla, California.
Robert B WallaceDepartment of Epidemiology, University of Iowa, Iowa City, Iowa.
Katherine W ReevesDepartment of Biostatistics and Epidemiology, University of Massachusetts Amherst, Amherst, Massachusetts. kwreeves@schoolph.umass.edu.
Amherst College · USUniversity of California San Diego · USUniversity of Iowa · US

Funding

Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI HANS-JOACHIM LEHMLER · 1990 to 2026
$40.5M
NHLBI NIH HHS HHSN268201600001CNHLBI NIH HHS HHSN268201600002CNHLBI NIH HHS HHSN268201600003CNHLBI NIH HHS HHSN268201600004CNHLBI NIH HHS HHSN268201600018CNIEHS NIH HHS P30 ES005605
6 · The paper itself

Abstract

backgroundPrior studies evaluating psychotropic medications in relation to breast cancer risk are inconsistent and have not separately evaluated invasive and

methodsWe estimated hazard ratios (HR) and 95% confidence intervals (CI) for the association of psychotropic medication use (any, typical antipsychotics, atypical antipsychotics, and lithium) with invasive and

resultsPrevalence of psychotropic medication use was low (

conclusionsThese findings do not support an association of psychotropic medication use with invasive breast cancer risk. The possible elevation in IMPACT: Our findings contribute to knowledge of the safety profile of psychotropic medications and may be useful to clinicians and patients considering use of these medications.

Indexed as

AgedBreastBreast Carcinoma In SituBreast NeoplasmsCarcinoma, Ductal, BreastFemaleFollow-Up StudiesHumansMammographyMiddle AgedPostmenopauseProportional Hazards ModelsPsychotropic DrugsRisk FactorsUnited StatesPsychotropic Drugs

Identifiers

PMID31685559
PMCPMC6954318
OpenAlexW2985785901

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.