Evidence map›Paper›PMID 31685474›Full record

ArticleAntimicrobial agents and chemotherapy2019

Minimal Cerebrospinal Fluid Concentration of Miltefosine despite Therapeutic Plasma Levels during the Treatment of Amebic Encephalitis.

Marguerite L Monogue, Durward Watson, Julie S Alexander, Dominick Cavuoti, Laura M Doyle, Michael Zhuo Wang, Bonnie C Prokesch

Open access · bronzeAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Identification of Potent and Selective Inhibitors ofJournal of medicinal chemistry · 2024
    Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Marguerite L MonogueDepartment of Pharmacy, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Durward WatsonDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Julie S AlexanderDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Dominick CavuotiDepartment of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Laura M DoyleDepartment of Pharmaceutical Chemistry, School of Pharmacy, University of Kansas, Lawrence, Kansas, USA.
Michael Zhuo WangDepartment of Pharmaceutical Chemistry, School of Pharmacy, University of Kansas, Lawrence, Kansas, USA.
Bonnie C ProkeschDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA bonnie.prokesch@utsouthwestern.edu.
The University of Texas Southwestern Medical Center · USUniversity of Kansas · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Miltefosine is an alkylphosphocholine compound that is used primarily for treatment of leishmaniasis and demonstrates

Indexed as

AcanthamoebaAdultAIDS-Related Opportunistic InfectionsAmebiasisAmebicidesBrainCentral Nervous System Protozoal InfectionsHumansInfectious EncephalitisMalePhosphorylcholineAmebicidesmiltefosinePhosphorylcholineAIDSamebacerebrospinal fluidHIVmiltefosine

Identifiers

PMID31685474
PMCPMC7187623
OpenAlexW2985083776

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.