Evidence map›Paper›PMID 31685462›Full record

ArticleAntimicrobial agents and chemotherapy2019

Influence of the α-Methoxy Group on the Reaction of Temocillin with Pseudomonas aeruginosa PBP3 and CTX-M-14 β-Lactamase.

Michael D Sacco, Kyle G Kroeck, M Trent Kemp, Xiujun Zhang, Logan D Andrews, Yu Chen

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.3field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Temocillin: A Narrative Review of Its Clinical Reappraisal.Antibiotics (Basel, Switzerland) · 2025
    Review
  5. Review
  6. Article
  7. Article
  8. ReducedJournal of clinical microbiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Michael D Sacco *Department of Molecular Medicine, University of South Florida, Tampa, Florida, USA.
Kyle G Kroeck *Department of Molecular Medicine, University of South Florida, Tampa, Florida, USA.
M Trent KempDepartment of Molecular Medicine, University of South Florida, Tampa, Florida, USA.
Xiujun ZhangDepartment of Molecular Medicine, University of South Florida, Tampa, Florida, USA.
Logan D AndrewsAchaogen, Inc., South San Francisco, California, USA logdrews@gmail.com ychen1@health.usf.edu.
Yu ChenDepartment of Molecular Medicine, University of South Florida, Tampa, Florida, USA logdrews@gmail.com ychen1@health.usf.edu.ORCID 0000-0002-5115-3600
University of South Florida · US

Funding

Evolution and inhibition of beta-lactamase activity in antibiotic resistanceR01AI103158 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI CHEN, YU · 2013 to 2017
$2.0M
Novel inhibitor discovery against Pseudomonas aeruginosa PBP3R21AI147654 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI CHEN, YU · 2019 to 2020
$411k
NIAID NIH HHS R01 AI103158NIAID NIH HHS R21 AI147654
6 · The paper itself

Abstract

The prevalence of multidrug-resistant

Indexed as

Anti-Bacterial Agentsbeta-Lactamasesbeta-LactamsMicrobial Sensitivity TestsPenicillin-Binding ProteinsPenicillinsPseudomonas aeruginosaTicarcillinAnti-Bacterial Agentsbeta-lactamase CTX-M-14beta-Lactamasesbeta-LactamsPenicillin-Binding ProteinsPenicillinstemocillinTicarcillinbeta-lactamasesbeta-lactamsPBP3penicillin-binding proteinsPseudomonas aeruginosatemocillinticarcillin

Identifiers

PMID31685462
PMCPMC7187628
OpenAlexW2982301258

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.